AutismKB 2.0

Annotation Details for GRB14


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Basic Information Top
Gene Symbol:GRB14 ( - )
Gene Full Name: growth factor receptor-bound protein 14
Band: 2q24.3
Quick LinksEntrez ID:2888; OMIM: 601524; Uniprot ID:GRB14_HUMAN; ENSEMBL ID: ENSG00000115290; HGNC ID: 4565
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm11278563
GO:0005829TAS-cytosol-
GO:0005886IDA-plasma membrane11278563
GO:0010008IEA-endosome membrane-
GO:0043231IDA-intracellular membrane-bounded organelle11278563
GO ID Evidence Qualifier GO_term References
GO:0005070IEA-SH3/SH2 adaptor activity-
GO:0030971IPI-receptor tyrosine kinase binding16246733
GO:0042802IMP-identical protein binding16246733
GO:0042803IMP-protein homodimerization activity16246733
GO ID Evidence Qualifier GO_term References
GO:0007165IEA-signal transduction-
GO:0009967IEA-positive regulation of signal transduction-
GO:0046627IMP-negative regulation of insulin receptor signaling pathway16246733
GO:0050900TAS-leukocyte migration-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GRB14DAPK310798312242277 Reconstituted Complex
GRB14DAPK310914512242277 Reconstituted Complex
GRB14EGFR1091458647858 Reconstituted Complex
GRB14EGFR1082768647858 Reconstituted Complex
GRB14FGFR110855110713090 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
GRB14FGFR110914510713090 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
PDGFRBGRB141111858647858 Reconstituted Complex
PDGFRBGRB141091458647858 Reconstituted Complex
TNKS2GRB1412325711278563 Affinity Capture-Western; Co-fractionation; Reconstituted Complex; Two-hybrid
TNKS2GRB1410914511278563 Affinity Capture-Western; Co-fractionation; Reconstituted Complex; Two-hybrid
FTCDGRB1411605311278563 Co-fractionation
FTCDGRB1410914511278563 Co-fractionation
INSRGRB1410985411726652 Affinity Capture-Western
INSRGRB1410914511726652 Affinity Capture-Western
PRKCZGRB1411157612242277 Affinity Capture-Western
PRKCZGRB1410914512242277 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
GRB14rs8192673, rs8192674 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:1355324
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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