AutismKB 2.0

Annotation Details for GRIA2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:GRIA2 ( GLUR2,GLURB,GluA2,GluR-K2,HBGR2 )
Gene Full Name: glutamate receptor, ionotropic, AMPA 2
Band: 4q32.1
Quick LinksEntrez ID:2891; OMIM: 138247; Uniprot ID:GRIA2_HUMAN; ENSEMBL ID: ENSG00000120251; HGNC ID: 4572
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005789IEA-endoplasmic reticulum membrane-
GO:0005886TAS-plasma membrane-
GO:0005887ISS-integral component of plasma membrane-
GO:0030054IEA-cell junction-
GO:0030666TAS-endocytic vesicle membrane-
GO:0032281IBA-AMPA glutamate receptor complex-
GO:0032281ISS-AMPA glutamate receptor complex-
GO:0045211IEA-postsynaptic membrane-
GO ID Evidence Qualifier GO_term References
GO:0004970IDA-ionotropic glutamate receptor activity20614889
GO:0004971IBA-AMPA glutamate receptor activity-
GO:0004971ISS-AMPA glutamate receptor activity-
GO:0005231TAS-excitatory extracellular ligand-gated ion channel activity-
GO:0005234IEA-extracellular-glutamate-gated ion channel activity-
GO:0005515IPI-protein binding12130635
GO ID Evidence Qualifier GO_term References
GO:0007165TAS-signal transduction8003671
GO:0007268TAS-chemical synaptic transmission8003671
GO:0034220IEA-ion transmembrane transport-
GO:0035235IDA-ionotropic glutamate receptor signaling pathway20614889
GO:0060079IEA-excitatory postsynaptic potential-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GRIA2DLG410914816990550 Affinity Capture-MS
GRIA2DLG410808616990550 Affinity Capture-MS
GRIA2GRIA110914710358037 Affinity Capture-Western
GRIA2GRIA110914810358037 Affinity Capture-Western
GRIK2GRIA21091558288598 Affinity Capture-Western
GRIK2GRIA21091488288598 Affinity Capture-Western
SPTAN1GRIA211258710576550 Affinity Capture-Western; Far Western
SPTAN1GRIA210914810576550 Affinity Capture-Western; Far Western
SPTBN1GRIA211258910576550 Far Western
SPTBN1GRIA210914810576550 Far Western
CACNG2GRIA211564811140673 Affinity Capture-Western
CACNG2GRIA210914811140673 Affinity Capture-Western
SDCBPGRIA211228711891216 Reconstituted Complex
SDCBPGRIA210914811891216 Reconstituted Complex
GRIP1GRIA210914811891216 Reconstituted Complex; Two-hybrid
GRIP1GRIA211699511891216 Reconstituted Complex; Two-hybrid
PICK1GRIA211484911891216 Reconstituted Complex; Two-hybrid
PICK1GRIA210914811891216 Reconstituted Complex; Two-hybrid
GRID2GRIA210914812573530 Affinity Capture-Western
GRID2GRIA210915212573530 Affinity Capture-Western
GRIK5GRIA210915812573530 Affinity Capture-Western
GRIK5GRIA210914812573530 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
GRIA2rs3813296, rs4260586, rs4302506, rs4441804, rs6536221 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:95809
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-020125-3'