AutismKB 2.0

Annotation Details for GIT1


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Basic Information Top
Gene Symbol:GIT1 ( - )
Gene Full Name: G protein-coupled receptor kinase interacting ArfGAP 1
Band: 17q11.2
Quick LinksEntrez ID:28964; OMIM: 608434; Uniprot ID:GIT1_HUMAN; ENSEMBL ID: ENSG00000108262; HGNC ID: 4272
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0005925IDA-focal adhesion21423176
GO:0016020IDA-membrane19946888
GO ID Evidence Qualifier GO_term References
GO:0005096IEA-GTPase activator activity-
GO:0005515IPI-protein binding15182672
GO:0032403IEA-protein complex binding-
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0008277TAS-regulation of G-protein coupled receptor protein signaling pathway9826657
GO:0032465IDA-regulation of cytokinesis23108400
GO:0043547IEA-positive regulation of GTPase activity-
GO:0048013TAS-ephrin receptor signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GIT1ADRBK11066659826657 10896954 Affinity Capture-Western
GIT1ADRBK11187899826657 10896954 Affinity Capture-Western
GIT1ADRBK21066669826657 Affinity Capture-Western
GIT1ADRBK21187899826657 Affinity Capture-Western
GIT1CAMK2A11878918292392 Affinity Capture-Western
GIT1CAMK2A10726518292392 Affinity Capture-Western
GIT1PTK2B10848012629171 Affinity Capture-Western
GIT1PTK2B11878912629171 Affinity Capture-Western
GIT1HMOX210940616169070 Two-hybrid
GIT1HMOX211878916169070 Two-hybrid
GIT1EIF611878916169070 Two-hybrid
GIT1EIF610989816169070 Two-hybrid
GIT1MAN2A211029516169070 Two-hybrid
GIT1MAN2A211878916169070 Two-hybrid
GIT1PAK211109817353931 Affinity Capture-MS
GIT1PAK211878917353931 Affinity Capture-MS
GIT1PFDN111122316169070 Two-hybrid
GIT1PFDN111878916169070 Two-hybrid
GIT1PLCG111135114523024 Affinity Capture-Western; Reconstituted Complex
GIT1PLCG111878914523024 Affinity Capture-Western; Reconstituted Complex
GIT1PTK211171910938112 12473661 12629171 Affinity Capture-Western; Reconstituted Complex
GIT1PTK211878910938112 12473661 12629171 Affinity Capture-Western; Reconstituted Complex
GIT1PTPRF11175612629171 Affinity Capture-Western
GIT1PTPRF11878912629171 Affinity Capture-Western
GIT1PTPRZ111878911381105 Affinity Capture-Western
GIT1PTPRZ111176711381105 Affinity Capture-Western
GIT1PXN11178712629171 Affinity Capture-Western
GIT1PXN11878912629171 Affinity Capture-Western
GIT1RGS211192916169070 Two-hybrid
GIT1RGS211878916169070 Two-hybrid
GIT1TERF111287216169070 Two-hybrid
GIT1TERF111878916169070 Two-hybrid
GIT1PPFIA411406912629171 12923177 Reconstituted Complex; Two-hybrid
GIT1PPFIA411878912629171 12923177 Reconstituted Complex; Two-hybrid
GIT1PPFIA211407112923177 Reconstituted Complex; Two-hybrid
GIT1PPFIA211878912923177 Reconstituted Complex; Two-hybrid
GIT1PPFIA111407212629171 12923177 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
GIT1PPFIA111878912629171 12923177 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
GIT1PPFIA311411112923177 Reconstituted Complex; Two-hybrid
GIT1PPFIA311878912923177 Reconstituted Complex; Two-hybrid
GIT1ARHGEF711439310428811 12473661 Affinity Capture-Western; Two-hybrid
GIT1ARHGEF711878910428811 12473661 Affinity Capture-Western; Two-hybrid
GIT1ARHGEF611484710428811 Affinity Capture-Western
GIT1ARHGEF611878910428811 Affinity Capture-Western
GIT1GIT211515412473661 Affinity Capture-Western; Two-hybrid
GIT1GIT211878912473661 Affinity Capture-Western; Two-hybrid
GIT1TXNDC911548716169070 Two-hybrid
GIT1TXNDC911878916169070 Two-hybrid
GIT1HBXIP11579616169070 Two-hybrid
GIT1HBXIP11878916169070 Two-hybrid
GIT1SDCCAG311602116169070 Two-hybrid
GIT1SDCCAG311878916169070 Two-hybrid
GIT1PMF111640516169070 Two-hybrid
GIT1PMF111878916169070 Two-hybrid
GIT1ERC211752112923177 Affinity Capture-Western
GIT1ERC211878912923177 Affinity Capture-Western
GIT1PCLO11817812473661 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
GIT1PCLO11878912473661 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
GIT1GIT111878912473661 Affinity Capture-Western; Co-fractionation; Two-hybrid
GRIP2GIT112333012629171 Affinity Capture-Western
GRIP2GIT111878912629171 Affinity Capture-Western
CCDC113GIT111884316169070 Two-hybrid
CCDC113GIT111878916169070 Two-hybrid
SRRTGIT111962616169070 Two-hybrid
SRRTGIT111878916169070 Two-hybrid
WDR33GIT112062016169070 Two-hybrid
WDR33GIT111878916169070 Two-hybrid
DDX24GIT112135316169070 Two-hybrid
DDX24GIT111878916169070 Two-hybrid
TRIB3GIT112175616169070 Two-hybrid
TRIB3GIT111878916169070 Two-hybrid
C8orf33GIT112242016169070 Two-hybrid
C8orf33GIT111878916169070 Two-hybrid
Gene Symbol Interactant Interaction ID References Description
GIT1PXN21777615793570 GIT1 interacts with Paxillin (PXN).
GIT1PPFIA213415712923177 Liprin-alpha2 interacts with GIT1. This interaction was modeled on a demonstrated interaction between human liprin-alpha2 and rat GIT1.
GIT1PPFIA313415812923177 Liprin-alpha3 interacts with GIT1. This interaction was modeled on a demonstrated interaction between human liprin-alpha3 and rat GIT1.
Gene Symbol Interactant Interaction ID References Description
GIT1TGFB1I10657712153727 -
GIT1TGFB1I10383112153727 -
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1927140
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-100408-5'