AutismKB 2.0

Annotation Details for GRIK1


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Basic Information Top
Gene Symbol:GRIK1 ( EAA3,EEA3,GLR5,GLUR5 )
Gene Full Name: glutamate receptor, ionotropic, kainate 1
Band: 21q21.3
Quick LinksEntrez ID:2897; OMIM: 138245; Uniprot ID:GRIK1_HUMAN; ENSEMBL ID: ENSG00000171189; HGNC ID: 4579
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane8260617
GO:0030054IEA-cell junction-
GO:0045211IEA-postsynaptic membrane-
GO ID Evidence Qualifier GO_term References
GO:0005234IEA-extracellular-glutamate-gated ion channel activity-
GO:0015276TAS-ligand-gated ion channel activity-
GO:0015277IDA-kainate selective glutamate receptor activity9335499
GO ID Evidence Qualifier GO_term References
GO:0006810TAS-transport8260617
GO:0007215TAS-glutamate receptor signaling pathway8260617
GO:0007268TAS-chemical synaptic transmission10580501
GO:0007399TAS-nervous system development8260617
GO:0007417TAS-central nervous system development10580501
GO:0034220IEA-ion transmembrane transport-
GO:0035235IEA-ionotropic glutamate receptor signaling pathway-
GO:0051966TAS-regulation of synaptic transmission, glutamatergic9335499
GO:0060079IEA-excitatory postsynaptic potential-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GRIK1DLG410915412597860 Affinity Capture-Western; Reconstituted Complex
GRIK1DLG410808612597860 Affinity Capture-Western; Reconstituted Complex
HOMER1GRIK111484511418862 Affinity Capture-Western
HOMER1GRIK110915411418862 Affinity Capture-Western
SDCBPGRIK111228712597860 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SDCBPGRIK110915412597860 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
PICK1GRIK111484912597860 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
PICK1GRIK110915412597860 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
GRIP1GRIK110915412597860 Reconstituted Complex
GRIP1GRIK111699512597860 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
GRIK1GRIK1_A2585G, rs363430, rs363504, rs363538 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:95814
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-6502'