AutismKB 2.0

Annotation Details for GRIK5


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Basic Information Top
Gene Symbol:GRIK5 ( EAA2,GRIK2,KA2 )
Gene Full Name: glutamate receptor, ionotropic, kainate 5
Band: 19q13.2
Quick LinksEntrez ID:2901; OMIM: 600283; Uniprot ID:GRIK5_HUMAN; ENSEMBL ID: ENSG00000105737; HGNC ID: 4583
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005783IEA-endoplasmic reticulum-
GO:0005886TAS-plasma membrane-
GO:0014069IEA-postsynaptic density-
GO:0030054IEA-cell junction-
GO:0030425IEA-dendrite-
GO:0032983IEA-kainate selective glutamate receptor complex-
GO:0042734IEA-presynaptic membrane-
GO:0043195IEA-terminal bouton-
GO:0043204IEA-perikaryon-
GO:0045211IEA-postsynaptic membrane-
GO ID Evidence Qualifier GO_term References
GO:0005234IEA-extracellular-glutamate-gated ion channel activity-
GO:0015276TAS-ligand-gated ion channel activity-
GO:0015277IDA-kainate selective glutamate receptor activity1321949
GO:0017124IEA-SH3 domain binding-
GO:0030165IEA-PDZ domain binding-
GO:0042802IEA-identical protein binding-
GO ID Evidence Qualifier GO_term References
GO:0006621IEA-protein retention in ER lumen-
GO:0031630IEA-regulation of synaptic vesicle fusion to presynaptic active zone membrane-
GO:0034220IEA-ion transmembrane transport-
GO:0035235IEA-ionotropic glutamate receptor signaling pathway-
GO:0035249IEA-synaptic transmission, glutamatergic-
GO:0043113IEA-receptor clustering-
GO:0043525IEA-positive regulation of neuron apoptotic process-
GO:0051649IEA-establishment of localization in cell-
GO:0060079IEA-excitatory postsynaptic potential-
GO:0071333IEA-cellular response to glucose stimulus-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GRIK5DLG31080859808460 Affinity Capture-Western
GRIK5DLG31091589808460 Affinity Capture-Western
GRIK5DLG41091589808460 11279111 Affinity Capture-Western; Reconstituted Complex
GRIK5DLG41080869808460 11279111 Affinity Capture-Western; Reconstituted Complex
GRIK5GRIA210915812573530 Affinity Capture-Western
GRIK5GRIA210914812573530 Affinity Capture-Western
GRIK5GRID210915812573530 Affinity Capture-Western
GRIK5GRID210915212573530 Affinity Capture-Western
GRIK5GRIK21091558288598 9466455 Affinity Capture-Western
GRIK5GRIK21091588288598 9466455 Affinity Capture-Western
GRIK5GRIK31091569466455 Affinity Capture-Western
GRIK5GRIK31091589466455 Affinity Capture-Western
MLF1GRIK510915816169070 Two-hybrid
MLF1GRIK511043716169070 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
GRIK5rs1056995, rs12463118, rs4803520, rs4803523, rs8099939 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:95818
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070821-6'