AutismKB 2.0

Annotation Details for GRIN2C


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:GRIN2C ( NMDAR2C,NR2C )
Gene Full Name: glutamate receptor, ionotropic, N-methyl D-aspartate 2C
Band: 17q25.1
Quick LinksEntrez ID:2905; OMIM: 138254; Uniprot ID:NMDE3_HUMAN; ENSEMBL ID: ENSG00000161509; HGNC ID: 4587
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005622IEA-intracellular-
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane9798920
GO:0014069IEA-postsynaptic density-
GO:0017146IEA-NMDA selective glutamate receptor complex-
GO:0030054IEA-cell junction-
GO:0045211IEA-postsynaptic membrane-
GO ID Evidence Qualifier GO_term References
GO:0004972IEA-NMDA glutamate receptor activity-
GO:0005088TAS-Ras guanyl-nucleotide exchange factor activity-
GO:0005234IEA-extracellular-glutamate-gated ion channel activity-
GO:0005515IPI-protein binding11937501
GO ID Evidence Qualifier GO_term References
GO:0000165TAS-MAPK cascade-
GO:0006810TAS-transport9798920
GO:0007215TAS-glutamate receptor signaling pathway9798920
GO:0008104IEA-protein localization-
GO:0009611IEA-response to wounding-
GO:0033058IEA-directional locomotion-
GO:0034765IEA-regulation of ion transmembrane transport-
GO:0035235IEA-ionotropic glutamate receptor signaling pathway-
GO:0042177IEA-negative regulation of protein catabolic process-
GO:0043547IEA-positive regulation of GTPase activity-
GO:0050885IEA-neuromuscular process controlling balance-
GO:0060079IEA-excitatory postsynaptic potential-
GO:0098655IEA-cation transmembrane transport-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GRIN2CDLG310916211937501 Affinity Capture-Western; Reconstituted Complex
GRIN2CDLG310808511937501 Affinity Capture-Western; Reconstituted Complex
GRIN2CDLG410916211937501 Affinity Capture-Western; Reconstituted Complex
GRIN2CDLG410808611937501 Affinity Capture-Western; Reconstituted Complex
IL16GRIN2C10981610479680 Two-hybrid
IL16GRIN2C10916210479680 Two-hybrid
ERBB2IPGRIN2C12099711278603 Reconstituted Complex
ERBB2IPGRIN2C10916211278603 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
GRIN2CGRIN2C_IVS3-70C/T, GRIN2C_IVS7-48A/G, GRIN2C_IVS8+69C/T Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:95822
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070822-3'