AutismKB 2.0

Annotation Details for MED4


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Basic Information Top
Gene Symbol:MED4 ( ARC36,DRIP36,FLJ10956,HSPC126,TRAP36,VDRIP )
Gene Full Name: mediator complex subunit 4
Band: 13q14.2
Quick LinksEntrez ID:29079; OMIM: 605718; Uniprot ID:MED4_HUMAN; ENSEMBL ID: ENSG00000136146; HGNC ID: 17903
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus10235267
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0016020IDA-membrane19946888
GO:0016592IDA-mediator complex10882111
GO:0070847IBA-core mediator complex-
GO ID Evidence Qualifier GO_term References
GO:0001104IDA-RNA polymerase II transcription cofactor activity10882111
GO:0003712IDA-transcription cofactor activity12218053
GO:0004872IDA-receptor activity12218053
GO:0005515IPI-protein binding14638676
GO:0030374NAS-ligand-dependent nuclear receptor transcription coactivator activity10235266
GO:0042809NAS-vitamin D receptor binding10235266
GO:0046966IDA-thyroid hormone receptor binding10198638
GO ID Evidence Qualifier GO_term References
GO:0006357IEA-regulation of transcription from RNA polymerase II promoter-
GO:0006366IDA-transcription from RNA polymerase II promoter10882111
GO:0006367IDA-transcription initiation from RNA polymerase II promoter12218053
GO:0006367TAS-transcription initiation from RNA polymerase II promoter-
GO:0030518IDA-intracellular steroid hormone receptor signaling pathway11867769
GO:0030521IDA-androgen receptor signaling pathway12218053
GO:0045893IDA-positive regulation of transcription, DNA-templated10198638
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MED4AP2M110758716189514 Two-hybrid
MED4AP2M111884916189514 Two-hybrid
MED4EMD11884917620012 Affinity Capture-MS
MED4EMD10832517620012 Affinity Capture-MS
MED4MED111884915989967 Affinity Capture-MS
MED4MED111146515989967 Affinity Capture-MS
MED4MED2611483115175163 Affinity Capture-MS
MED4MED2611884915175163 Affinity Capture-MS
MED4MCRS111571016189514 Two-hybrid
MED4MCRS111884916189514 Two-hybrid
MED4TNFAIP811734416189514 Two-hybrid
MED4TNFAIP811884916189514 Two-hybrid
MED30MED412470712584197 Reconstituted Complex
MED30MED411884912584197 Reconstituted Complex
MED19MED412855314638676 15175163 Affinity Capture-MS; Affinity Capture-Western
MED19MED411884914638676 15175163 Affinity Capture-MS; Affinity Capture-Western
MED29MED411884914638676 15175163 Affinity Capture-MS; Affinity Capture-Western
MED29MED412073414638676 15175163 Affinity Capture-MS; Affinity Capture-Western
MED10MED412397414638676 15175163 15989967 Affinity Capture-MS; Affinity Capture-Western
MED10MED411884914638676 15175163 15989967 Affinity Capture-MS; Affinity Capture-Western
MED25MED412360714638676 Affinity Capture-Western; Reconstituted Complex
MED25MED411884914638676 Affinity Capture-Western; Reconstituted Complex
MED9MED412040315175163 Affinity Capture-MS
MED9MED411884915175163 Affinity Capture-MS
MED28MED412321915175163 Affinity Capture-MS
MED28MED411884915175163 Affinity Capture-MS
RPAP2MED412295917643375 Affinity Capture-MS
RPAP2MED411884917643375 Affinity Capture-MS
MED18MED412015618250152 Affinity Capture-Western
MED18MED411884918250152 Affinity Capture-Western
PCBD2MED412389320211142 Two-hybrid
PCBD2MED411884920211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1914631
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-050417-438'