AutismKB 2.0

Annotation Details for DROSHA


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Basic Information Top
Gene Symbol:DROSHA ( ETOHI2,HSA242976,RANSE3L,RN3,RNASE3L,RNASEN )
Gene Full Name: drosha, ribonuclease type III
Band: 5p13.3
Quick LinksEntrez ID:29102; OMIM: 608828; Uniprot ID:RNC_HUMAN; ENSEMBL ID: ENSG00000113360; HGNC ID: 17904
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus-
GO:0005654TAS-nucleoplasm-
GO:0005730IEA-nucleolus-
GO:0005886IDA-plasma membrane-
GO:0005925IDA-focal adhesion-
GO:0070877IDA-microprocessor complex15574589
GO ID Evidence Qualifier GO_term References
GO:0001530IDA-lipopolysaccharide binding20180804
GO:0003723IDA-RNA binding22658674
GO:0004525IDA-ribonuclease III activity14508493
GO:0005515IPI-protein binding15574589
GO:0017151IPI-DEAD/H-box RNA helicase binding18548003
GO:0042803IDA-protein homodimerization activity15574589
GO:0046332IPI-SMAD binding18548003
GO:0046872IEA-metal ion binding-
GO:0070412IPI-R-SMAD binding18548003
GO:0070878IPI-primary miRNA binding18548003
GO:0070878NAS-primary miRNA binding15574589
GO ID Evidence Qualifier GO_term References
GO:0010586TAS-miRNA metabolic process-
GO:0010628IEA-positive regulation of gene expression-
GO:0016075IEA-rRNA catabolic process-
GO:0031053IDA-primary miRNA processing14508493
GO:0031053IMP-primary miRNA processing14508493
GO:0031054IEA-pre-miRNA processing-
GO:0042254IEA-ribosome biogenesis-
GO:0045589IEA-regulation of regulatory T cell differentiation-
GO:0050727IEA-regulation of inflammatory response-
GO:0050829IDA-defense response to Gram-negative bacterium20180804
GO:0050830IDA-defense response to Gram-positive bacterium20180804
GO:0090502IEA-RNA phosphodiester bond hydrolysis, endonucleolytic-
GO:2000628IEA-regulation of miRNA metabolic process-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1261425
  • Data Attributes: HomoloGene calculated
No data