AutismKB 2.0

Annotation Details for CTNNA3


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Basic Information Top
Gene Symbol:CTNNA3 ( MGC26194,MGC75041,VR22 )
Gene Full Name: catenin (cadherin-associated protein), alpha 3
Band: 10q21.3
Quick LinksEntrez ID:29119; OMIM: 607667; Uniprot ID:CTNA3_HUMAN; ENSEMBL ID: ENSG00000183230; HGNC ID: 2511
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IEA-cytoplasm-
GO:0005856IEA-cytoskeleton-
GO:0005916IDA-fascia adherens11590244
GO:0030027IEA-lamellipodium-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding11590244
GO:0008013IPI-beta-catenin binding23136403
GO:0045296TAS-cadherin binding11590244
GO:0051015IEA-actin filament binding-
GO:0086083IMP-cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication23136403
GO ID Evidence Qualifier GO_term References
GO:0016337IPI-single organismal cell-cell adhesion11590244
GO:0086073IMP-bundle of His cell-Purkinje myocyte adhesion involved in cell communication23136403
GO:0086091IMP-regulation of heart rate by cardiac conduction23136403
GO:0098911IMP-regulation of ventricular cardiac muscle cell action potential23136403
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CTNNA3CTNNB111888511590244 Affinity Capture-Western
CTNNA3CTNNB110788011590244 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
VR22rs10822890, rs10996886, rs10997307, rs10997691, rs12258078, rs12357560, rs1786927, rs2105702, rs2126750, rs2306402, rs2394287, rs2441718, rs2456737, rs3096244, rs3750863, rs4459178, rs4548513, rs6480140, rs7070570, rs7074454, rs713250, rs7909676, rs7911820, rs997225 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:2661445
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018