AutismKB 2.0

Annotation Details for GRM2


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Basic Information Top
Gene Symbol:GRM2 ( GLUR2,GPRC1B,MGLUR2,mGlu2 )
Gene Full Name: glutamate receptor, metabotropic 2
Band: 3p21.2
Quick LinksEntrez ID:2912; OMIM: 604099; Uniprot ID:GRM2_HUMAN; ENSEMBL ID: ENSG00000164082; HGNC ID: 4594
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005622IEA-intracellular-
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane7620613
GO:0030054IEA-cell junction-
GO:0030424IEA-axon-
GO:0030425IEA-dendrite-
GO:0042734IEA-presynaptic membrane-
GO ID Evidence Qualifier GO_term References
GO:0001641IEA-group II metabotropic glutamate receptor activity-
GO:0004930TAS-G-protein coupled receptor activity7620613
GO:0005246IBA-calcium channel regulator activity-
GO:0005515IPI-protein binding25416956
GO:0008066TAS-glutamate receptor activity7620613
GO ID Evidence Qualifier GO_term References
GO:0007194TAS-negative regulation of adenylate cyclase activity7620613
GO:0007196IEA-adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway-
GO:0007216IBA-G-protein coupled glutamate receptor signaling pathway-
GO:0007268TAS-chemical synaptic transmission7620613
GO:0014047IEA-glutamate secretion-
GO:0051966IBA-regulation of synaptic transmission, glutamatergic-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
GRM2GRM2_-34A/C, rs12487957, rs4687771 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:1351339
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-060201-5'