Annotation Details for GRM7
Basic Information Top
| Gene Symbol: | GRM7 ( FLJ40498,GLUR7,GPRC1G,MGLU7,MGLUR7 ) |
|---|---|
| Gene Full Name: | glutamate receptor, metabotropic 7 |
| Band: | 3p26.1 |
| Quick Links | Entrez ID:2917; OMIM: 604101; Uniprot ID:GRM7_HUMAN; ENSEMBL ID: ENSG00000196277; HGNC ID: 4599 |
| Relate to Another Database: | SFARIGene; denovo-db |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0005886 | TAS | - | plasma membrane | - |
| GO:0005887 | IBA | - | integral component of plasma membrane | - |
| GO:0005887 | NAS | - | integral component of plasma membrane | 9473604 |
| GO:0005938 | IDA | - | cell cortex | 9630572 |
| GO:0016021 | IDA | - | integral component of membrane | 12746871 |
| GO:0030424 | ISS | - | axon | - |
| GO:0030425 | IDA | - | dendrite | 9630572 |
| GO:0032279 | ISS | - | asymmetric synapse | - |
| GO:0042734 | IBA | - | presynaptic membrane | - |
| GO:0043198 | ISS | - | dendritic shaft | - |
| GO:0043235 | IDA | - | receptor complex | 23382219 |
| GO:0045211 | ISS | - | postsynaptic membrane | - |
| GO:0048786 | ISS | - | presynaptic active zone | - |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0001642 | IDA | - | group III metabotropic glutamate receptor activity | 9144652 |
| GO:0005246 | IBA | - | calcium channel regulator activity | - |
| GO:0008066 | IDA | - | glutamate receptor activity | 9473604 |
| GO:0010855 | IDA | - | adenylate cyclase inhibitor activity | 9473604 |
| GO:0070905 | IDA | - | serine binding | 9144652 |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0001662 | IMP | NOT | behavioral fear response | 17167337 |
| GO:0007196 | IDA | - | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway | 9473604 |
| GO:0007268 | IDA | - | chemical synaptic transmission | 9473604 |
| GO:0007605 | IMP | - | sensory perception of sound | 19047183 |
| GO:0007608 | IEA | - | sensory perception of smell | - |
| GO:0014050 | ISS | - | negative regulation of glutamate secretion | - |
| GO:0030818 | IDA | - | negative regulation of cAMP biosynthetic process | 9473604 |
| GO:0031279 | IEA | - | regulation of cyclase activity | - |
| GO:0051966 | IBA | - | regulation of synaptic transmission, glutamatergic | - |
| Gene Symbol | Interactant | Interaction ID | References | Description |
|---|---|---|---|---|
| GRM7 | GNAQ | 109038 | 10550060 | Reconstituted Complex |
| GRM7 | GNAQ | 109174 | 10550060 | Reconstituted Complex |
| PRKCA | GRM7 | 109174 | 11007882 | Affinity Capture-Western |
| PRKCA | GRM7 | 111564 | 11007882 | Affinity Capture-Western |
| PICK1 | GRM7 | 109174 | 11007882 | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid |
| PICK1 | GRM7 | 114849 | 11007882 | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid |
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| Gene Symbol | Poly Names | Gene overview in SZGene |
|---|---|---|
| GRM7 | GRM7_1536A/T, GRM7_2912T/C, GRM7_IVS9e+97C/T, rs1021687, rs1154352, rs11710715, rs11719710, rs11915789, rs1240966, rs12491620, rs1354407, rs1391947, rs1396404, rs1396409, rs1450099, rs1485170, rs1485174, rs1485175, rs1485179, rs1499077, rs1499149, rs1504045, rs1508707, rs1508722, rs1543146, rs1566367, rs1568075, rs1569286, rs1603876, rs162723, rs162777, rs162802, rs163422, rs17031835, rs17047896, rs2055737, rs2063882, rs2133450, rs2229902, rs2280739, rs323482, rs339023, rs339804, rs342016, rs342026, rs3749380, rs3749448, rs3749449, rs3749450, rs3792454, rs3804846, rs3840229, rs465152, rs4686101, rs490239, rs535146, rs6443102, rs6804571, rs6806817, rs712767, rs712774, rs712778, rs7609676, rs7644436, rs779746, rs882226, rs9826579, rs9883277 | Gene overview in SZGene |