AutismKB 2.0

Annotation Details for GSTM2


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Basic Information Top
Gene Symbol:GSTM2 ( GST4,GSTM,GSTM2-2,GTHMUS,MGC117303 )
Gene Full Name: glutathione S-transferase mu 2 (muscle)
Band: 1p13.3
Quick LinksEntrez ID:2946; OMIM: 138380; Uniprot ID:GSTM2_HUMAN; ENSEMBL ID: ENSG00000213366; HGNC ID: 4634
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm2034681
GO:0005829TAS-cytosol-
GO:0016529IDA-sarcoplasmic reticulum22406107
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0004364IDA-glutathione transferase activity2034681
GO:0004364TAS-glutathione transferase activity-
GO:0004602IDA-glutathione peroxidase activity16624487
GO:0005102IPI-receptor binding22406107
GO:0005515IPI-protein binding24965446
GO:0019899IPI-enzyme binding8373352
GO:0042803IPI-protein homodimerization activity8373352
GO:0043295IDA-glutathione binding2034681
GO ID Evidence Qualifier GO_term References
GO:0006749IDA-glutathione metabolic process2034681
GO:0010880IDA-regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum17023043
GO:0010881IC-regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion17023043
GO:0014809IC-regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion17023043
GO:0018916IDA-nitrobenzene metabolic process2034681
GO:0042178IDA-xenobiotic catabolic process2034681
GO:0043651IDA-linoleic acid metabolic process16624487
GO:0055119TAS-relaxation of cardiac muscle21323602
GO:0060315IDA-negative regulation of ryanodine-sensitive calcium-release channel activity17023043
GO:0060316IDA-positive regulation of ryanodine-sensitive calcium-release channel activity17023043
GO:0070458IDA-cellular detoxification of nitrogen compound2034681
GO:0071313IDA-cellular response to caffeine22406107
GO:0098869IEA-cellular oxidant detoxification-
GO:1901687TAS-glutathione derivative biosynthetic process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GSTM2GSTM110919912192076 Reconstituted Complex
GSTM2GSTM110920112192076 Reconstituted Complex
GSTM2GSTM210920112192076 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:95861
  • Data Attributes: MGI curated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018