AutismKB 2.0

Annotation Details for GTF2A2


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Basic Information Top
Gene Symbol:GTF2A2 ( HsT18745,TF2A2,TFIIA )
Gene Full Name: general transcription factor IIA, 2, 12kDa
Band: 15q22.2
Quick LinksEntrez ID:2958; OMIM: 600519; Uniprot ID:T2AG_HUMAN; ENSEMBL ID: ENSG00000140307; HGNC ID: 4647
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005669IDA-transcription factor TFIID complex27193682
GO:0005672IDA-transcription factor TFIIA complex7724559
GO:0030054IDA-cell junction-
GO ID Evidence Qualifier GO_term References
GO:0001103IEA-RNA polymerase II repressing transcription factor binding-
GO:0003713IDA-transcription coactivator activity7958899
GO:0005515IPI-protein binding7724559
GO:0008134IPI-transcription factor binding8626665
GO:0017025IPI-TBP-class protein binding7724559
GO:0042803IPI-protein homodimerization activity8626665
GO:0046982IPI-protein heterodimerization activity8626665
GO ID Evidence Qualifier GO_term References
GO:0006366IDA-transcription from RNA polymerase II promoter7724559
GO:0006366TAS-transcription from RNA polymerase II promoter-
GO:0006367TAS-transcription initiation from RNA polymerase II promoter-
GO:0006368TAS-transcription elongation from RNA polymerase II promoter-
GO:0016032IEA-viral process-
GO:0042795TAS-snRNA transcription from RNA polymerase II promoter-
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter7958899
GO:0051091IDA-positive regulation of sequence-specific DNA binding transcription factor activity8626665
GO:0051123IDA-RNA polymerase II transcriptional preinitiation complex assembly7958899
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GTF2A2GTF2A110921217643375 Affinity Capture-MS
GTF2A2GTF2A110921317643375 Affinity Capture-MS
TBPGTF2A21092137724559 7958900 9603936 Reconstituted Complex
TBPGTF2A21127717724559 7958900 9603936 Reconstituted Complex
TAF4GTF2A211273711564872 Reconstituted Complex
TAF4GTF2A210921311564872 Reconstituted Complex
TBPL1GTF2A211489617353931 17643375 Affinity Capture-MS
TBPL1GTF2A210921317353931 17643375 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1933289
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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