AutismKB 2.0

Annotation Details for GTF2H1


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Basic Information Top
Gene Symbol:GTF2H1 ( BTF2,TFB1,TFIIH )
Gene Full Name: general transcription factor IIH, polypeptide 1, 62kDa
Band: 11p15.1
Quick LinksEntrez ID:2965; OMIM: 189972; Uniprot ID:TF2H1_HUMAN; ENSEMBL ID: ENSG00000110768; HGNC ID: 4655
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000439IBA-core TFIIH complex-
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005675IDA-holo TFIIH complex9852112
GO ID Evidence Qualifier GO_term References
GO:0003682IEA-chromatin binding-
GO:0004672IDAcontributes_toprotein kinase activity9852112
GO:0005515IPI-protein binding8652557
GO:0008094IDAcontributes_toDNA-dependent ATPase activity9852112
GO:0008353IDAcontributes_toRNA polymerase II carboxy-terminal domain kinase activity9852112
GO ID Evidence Qualifier GO_term References
GO:0000079TAS-regulation of cyclin-dependent protein serine/threonine kinase activity7533895
GO:0000717TAS-nucleotide-excision repair, DNA duplex unwinding-
GO:0006281TAS-DNA repair9118947
GO:0006283TAS-transcription-coupled nucleotide-excision repair-
GO:0006293TAS-nucleotide-excision repair, preincision complex stabilization-
GO:0006294TAS-nucleotide-excision repair, preincision complex assembly-
GO:0006295TAS-nucleotide-excision repair, DNA incision, 3'-to lesion-
GO:0006296TAS-nucleotide-excision repair, DNA incision, 5'-to lesion-
GO:0006360IBA-transcription from RNA polymerase I promoter-
GO:0006361TAS-transcription initiation from RNA polymerase I promoter-
GO:0006362TAS-transcription elongation from RNA polymerase I promoter-
GO:0006363TAS-termination of RNA polymerase I transcription-
GO:0006366IDA-transcription from RNA polymerase II promoter9852112
GO:0006366TAS-transcription from RNA polymerase II promoter-
GO:0006367TAS-transcription initiation from RNA polymerase II promoter-
GO:0006368TAS-transcription elongation from RNA polymerase II promoter-
GO:0006370TAS-7-methylguanosine mRNA capping-
GO:0033683TAS-nucleotide-excision repair, DNA incision-
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter8692841
GO:0070816IBA-phosphorylation of RNA polymerase II C-terminal domain-
GO:0070911TAS-global genome nucleotide-excision repair-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GTF2H1AR10922010734072 Affinity Capture-Western
GTF2H1AR10686210734072 Affinity Capture-Western
GTF2H1CCNH1092207533895 Co-purification
GTF2H1CCNH1073427533895 Co-purification
GTF2H1CDK71092207533895 8521393 9130708 Affinity Capture-Western; Co-purification
GTF2H1CDK71074577533895 8521393 9130708 Affinity Capture-Western; Co-purification
GTF2H1E2F110820110428966 Affinity Capture-Western; Biochemical Activity
GTF2H1E2F110922010428966 Affinity Capture-Western; Biochemical Activity
GTF2H1ERCC21092208152490 9130708 Affinity Capture-Western; Reconstituted Complex
GTF2H1ERCC21083808152490 9130708 Affinity Capture-Western; Reconstituted Complex
GTF2H1ERCC31092209118947 9130708 15220921 17643375 Affinity Capture-MS; Affinity Capture-Western; Co-purification
GTF2H1ERCC31083839118947 9130708 15220921 17643375 Affinity Capture-MS; Affinity Capture-Western; Co-purification
GTF2H1ESR110922010949034 Biochemical Activity; Reconstituted Complex
GTF2H1ESR110840310949034 Biochemical Activity; Reconstituted Complex
TP53GTF2H11130107935417 Reconstituted Complex
TP53GTF2H11092207935417 Reconstituted Complex
TCEA1GTF2H11127799305922 9765293 Reconstituted Complex
TCEA1GTF2H11092209305922 9765293 Reconstituted Complex
GTF2H2GTF2H110922111062469 Affinity Capture-Western
GTF2H2GTF2H110922011062469 Affinity Capture-Western
PSMC2GTF2H111167411118327 Affinity Capture-Western
PSMC2GTF2H110922011118327 Affinity Capture-Western
FUBP1GTF2H111439911239393 Affinity Capture-Western
FUBP1GTF2H110922011239393 Affinity Capture-Western
TXNRD2GTF2H110922015625236 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TXNRD2GTF2H111583615625236 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RXRBGTF2H110922015625236 Reconstituted Complex; Two-hybrid
RXRBGTF2H111216915625236 Reconstituted Complex; Two-hybrid
FAM190BGTF2H111996816169070 Two-hybrid
FAM190BGTF2H110922016169070 Two-hybrid
JDP2GTF2H112580720211142 Two-hybrid
JDP2GTF2H110922020211142 Two-hybrid
ZSCAN1GTF2H112982520211142 Two-hybrid
ZSCAN1GTF2H110922020211142 Two-hybrid
HOXC11GTF2H110946720211142 Two-hybrid
HOXC11GTF2H110922020211142 Two-hybrid
POU2AF1GTF2H111144620211142 Two-hybrid
POU2AF1GTF2H110922020211142 Two-hybrid
BRPF1GTF2H111361420211142 Two-hybrid
BRPF1GTF2H110922020211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1277216
  • Data Attributes: MGI curated and HomoloGene calculated
No data