AutismKB 2.0

Annotation Details for GUCY1A2


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Basic Information Top
Gene Symbol:GUCY1A2 ( GC-SA2,GUC1A2 )
Gene Full Name: guanylate cyclase 1, soluble, alpha 2
Band: 11q22.3
Quick LinksEntrez ID:2977; OMIM: 601244; Uniprot ID:GCYA2_HUMAN; ENSEMBL ID: ENSG00000152402; HGNC ID: 4684
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886IBA-plasma membrane-
GO:0008074IBA-guanylate cyclase complex, soluble-
GO ID Evidence Qualifier GO_term References
GO:0004016IBANOTadenylate cyclase activity-
GO:0004383IBA-guanylate cyclase activity-
GO:0005515IPI-protein binding24550280
GO:0005525IEA-GTP binding-
GO:0020037IEA-heme binding-
GO ID Evidence Qualifier GO_term References
GO:0006182IBA-cGMP biosynthetic process-
GO:0007165TAS-signal transduction1683630
GO:0030828IEA-positive regulation of cGMP biosynthetic process-
GO:0035556IEA-intracellular signal transduction-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GUCY1A2DLG110808311572861 Affinity Capture-Western
GUCY1A2DLG110923211572861 Affinity Capture-Western
GUCY1A2DLG210808411572861 Affinity Capture-Western
GUCY1A2DLG210923211572861 Affinity Capture-Western
GUCY1A2DLG310923211572861 Affinity Capture-Western
GUCY1A2DLG310808511572861 Affinity Capture-Western
GUCY1A2DLG410923211572861 Affinity Capture-Western
GUCY1A2DLG410808611572861 Affinity Capture-Western
GUCY1B3GUCY1A210923211572861 Affinity Capture-Western
GUCY1B3GUCY1A210923811572861 Affinity Capture-Western
HSPA4GUCY1A210954017873020 Affinity Capture-Western
HSPA4GUCY1A210923217873020 Affinity Capture-Western
HSP90AA1GUCY1A210923217873020 Affinity Capture-Western
HSP90AA1GUCY1A210955217873020 Affinity Capture-Western
UBCGUCY1A210923217873020 Affinity Capture-Western
UBCGUCY1A211316417873020 Affinity Capture-Western
STUB1GUCY1A210923217873020 Affinity Capture-Western; Biochemical Activity
STUB1GUCY1A211556317873020 Affinity Capture-Western; Biochemical Activity
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2660877
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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