AutismKB 2.0

Annotation Details for CNOT7


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Basic Information Top
Gene Symbol:CNOT7 ( CAF1,hCAF-1 )
Gene Full Name: CCR4-NOT transcription complex, subunit 7
Band: 8p22
Quick LinksEntrez ID:29883; OMIM: 604913; Uniprot ID:CNOT7_HUMAN; ENSEMBL ID: ENSG00000198791; HGNC ID: 14101
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000932ISS-P-body-
GO:0005634IDA-nucleus9820826
GO:0005829TAS-cytosol-
GO:0016020IDA-membrane19946888
GO:0016604IDA-nuclear body-
GO:0030014IDA-CCR4-NOT complex19558367
GO:0030014NAS-CCR4-NOT complex9820826
GO ID Evidence Qualifier GO_term References
GO:0000175IDA-3'-5'-exoribonuclease activity15769875
GO:0003700TAS-transcription factor activity, sequence-specific DNA binding9820826
GO:0003723IEA-RNA binding-
GO:0004532IDA-exoribonuclease activity19276069
GO:0004535IDA-poly(A)-specific ribonuclease activity15769875
GO:0004871TAS-signal transducer activity9820826
GO:0005515IPI-protein binding9820826
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0000289TAS-nuclear-transcribed mRNA poly(A) tail shortening-
GO:0000290IEA-deadenylation-dependent decapping of nuclear-transcribed mRNA-
GO:0005975TAS-carbohydrate metabolic process9820826
GO:0006351IEA-transcription, DNA-templated-
GO:0006977TAS-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-
GO:0007165TAS-signal transduction9820826
GO:0008284IMP-positive regulation of cell proliferation19605561
GO:0008285IDA-negative regulation of cell proliferation19276069
GO:0010629IMP-negative regulation of gene expression25038453
GO:0031047ISS-gene silencing by RNA-
GO:0033962IEA-cytoplasmic mRNA processing body assembly-
GO:0035195TAS-gene silencing by miRNA20065043
GO:0043928IDA-exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay20065043
GO:0045944IEA-positive regulation of transcription from RNA polymerase II promoter-
GO:0060213IMP-positive regulation of nuclear-transcribed mRNA poly(A) tail shortening21278420
GO:0061014IMP-positive regulation of mRNA catabolic process25038453
GO:0090503IEA-RNA phosphodiester bond hydrolysis, exonucleolytic-
GO:1900153IMP-positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay21278420
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CNOT7BTG11071599820826 11136725 Reconstituted Complex; Two-hybrid
CNOT7BTG11189389820826 11136725 Reconstituted Complex; Two-hybrid
CNOT7CDK111893810602502 Affinity Capture-Western
CNOT7CDK110742010602502 Affinity Capture-Western
CNOT7CDK211893810602502 Affinity Capture-Western
CNOT7CDK210745210602502 Affinity Capture-Western
CNOT7CDK411893810602502 Affinity Capture-Western
CNOT7CDK410745410602502 Affinity Capture-Western
CNOT7HOXD411893820211142 Two-hybrid
CNOT7HOXD410947320211142 Two-hybrid
CNOT7BTG211893811136725 Reconstituted Complex
CNOT7BTG211359311136725 Reconstituted Complex
CNOT7IKBKG11893820098747 Reconstituted Complex
CNOT7IKBKG11408920098747 Reconstituted Complex
CNOT7TOB111893810602502 18056425 Affinity Capture-Western; Reconstituted Complex
CNOT7TOB111544310602502 18056425 Affinity Capture-Western; Reconstituted Complex
CNOT7TOB211893810602502 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
CNOT7TOB211598510602502 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
CNOT7PABPC111893818056425 Affinity Capture-Western; Reconstituted Complex
CNOT7PABPC111793918056425 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1298230
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-061013-29'