AutismKB 2.0

Annotation Details for SEC61A1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SEC61A1 ( HSEC61,SEC61,SEC61A )
Gene Full Name: Sec61 alpha 1 subunit (S. cerevisiae)
Band: 3q21.3
Quick LinksEntrez ID:29927; OMIM: 609213; Uniprot ID:S61A1_HUMAN; ENSEMBL ID: ENSG00000058262; HGNC ID: 18276
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005789IDA-endoplasmic reticulum membrane27392076
GO:0005791IEA-rough endoplasmic reticulum-
GO:0005829TAS-cytosol-
GO:0016020IDA-membrane22375059
GO:0030176ISS-integral component of endoplasmic reticulum membrane-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding22314232
GO:0043022ISS-ribosome binding-
GO ID Evidence Qualifier GO_term References
GO:0006614IMP-SRP-dependent cotranslational protein targeting to membrane22375059
GO:0006620IMP-posttranslational protein targeting to endoplasmic reticulum membrane22375059
GO:0007029IMP-endoplasmic reticulum organization22375059
GO:0016049IMP-cell growth22375059
GO:0034341IEA-response to interferon-gamma-
GO:0036498TAS-IRE1-mediated unfolded protein response-
GO:0039019ISS-pronephric nephron development-
GO:0045047ISS-protein targeting to ER-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SEC61A1APOB1189689565615 Affinity Capture-Western
SEC61A1APOB1068359565615 Affinity Capture-Western
SEC61A1AP1S110758817353931 Affinity Capture-MS
SEC61A1AP1S111896817353931 Affinity Capture-MS
SEC61A1NDN11896817353931 Affinity Capture-MS
SEC61A1NDN11077217353931 Affinity Capture-MS
SEC61A1USP1111386619615732 Affinity Capture-MS
SEC61A1USP1111896819615732 Affinity Capture-MS
SEC61A1USP1911607819615732 Affinity Capture-MS
SEC61A1USP1911896819615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
SEC61A1rs2075402 Gene overview in PDGene
No data
Animal Model Top
  • MGI ID: MGI:1858417
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved