AutismKB 2.0

Annotation Details for ANAPC4


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Basic Information Top
Gene Symbol:ANAPC4 ( APC4 )
Gene Full Name: anaphase promoting complex subunit 4
Band: 4p15.2
Quick LinksEntrez ID:29945; OMIM: 606947; Uniprot ID:APC4_HUMAN; ENSEMBL ID: ENSG00000053900; HGNC ID: 19990
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus21241890
GO:0005654TAS-nucleoplasm-
GO:0005680IDA-anaphase-promoting complex16364912
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0004842TAS-ubiquitin-protein transferase activity6180011
GO:0005515IPI-protein binding23288039
GO:0019903IPI-protein phosphatase binding21241890
GO ID Evidence Qualifier GO_term References
GO:0030071IEA-regulation of mitotic metaphase/anaphase transition-
GO:0031145TAS-anaphase-promoting complex-dependent catabolic process-
GO:0042787TAS-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-
GO:0043161TAS-proteasome-mediated ubiquitin-dependent protein catabolic process-
GO:0051301IEA-cell division-
GO:0051436TAS-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-
GO:0051437TAS-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-
GO:0051439TAS-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-
GO:0070979IDA-protein K11-linked ubiquitination18485873
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ANAPC4CDC2711898210922056 12956947 14657031 Affinity Capture-MS; Affinity Capture-Western
ANAPC4CDC2710743110922056 12956947 14657031 Affinity Capture-MS; Affinity Capture-Western
ANAPC4CDH111898212956947 Reconstituted Complex
ANAPC4CDH110743412956947 Reconstituted Complex
ANAPC4CDC2311424212956947 Affinity Capture-Western
ANAPC4CDC2311898212956947 Affinity Capture-Western
ANAPC4CDC1611440012956947 Affinity Capture-Western
ANAPC4CDC1611898212956947 Affinity Capture-Western
ANAPC4APC211898212956947 Affinity Capture-Western
ANAPC4ANAPC1011566512956947 Affinity Capture-Western
ANAPC4ANAPC1011898212956947 Affinity Capture-Western
ANAPC4ANAPC211898212956947 Reconstituted Complex
ANAPC4ANAPC211893712956947 Reconstituted Complex
ANAPC1ANAPC412222911076961 12956947 Affinity Capture-Western; Co-purification; Reconstituted Complex
ANAPC1ANAPC411898211076961 12956947 Affinity Capture-Western; Co-purification; Reconstituted Complex
ANAPC5ANAPC411953712956947 Affinity Capture-Western; Reconstituted Complex
ANAPC5ANAPC411898212956947 Affinity Capture-Western; Reconstituted Complex
ANAPC7ANAPC411898212956947 Affinity Capture-Western; Reconstituted Complex
ANAPC7ANAPC411953812956947 Affinity Capture-Western; Reconstituted Complex
FZR1ANAPC411948912956947 Reconstituted Complex
FZR1ANAPC411898212956947 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1098673
  • Data Attributes: MGI curated and HomoloGene calculated
No data