AutismKB 2.0

Annotation Details for SLC40A1


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Basic Information Top
Gene Symbol:SLC40A1 ( FPN1,HFE4,IREG1,MST079,MTP1,SLC11A3 )
Gene Full Name: solute carrier family 40 (iron-regulated transporter), member 1
Band: 2q32.2
Quick LinksEntrez ID:30061; OMIM: 604653; Uniprot ID:S40A1_HUMAN; ENSEMBL ID: ENSG00000138449; HGNC ID: 10909
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005622IDA-intracellular20019163
GO:0005654IDA-nucleoplasm-
GO:0005737TAS-cytoplasm10747949
GO:0005829IDA-cytosol-
GO:0005886IDA-plasma membrane20019163
GO:0005886TAS-plasma membrane-
GO:0005887IC-integral component of plasma membrane12091367
GO:0008021IEA-synaptic vesicle-
GO:0016021TAS-integral component of membrane10747949
GO:0016323IDA-basolateral plasma membrane20019163
GO:0016323ISS-basolateral plasma membrane-
GO ID Evidence Qualifier GO_term References
GO:0004872ISS-receptor activity-
GO:0005381IMP-iron ion transmembrane transporter activity12091367
GO:0005515IPI-protein binding20817278
GO:0015093ISS-ferrous iron transmembrane transporter activity-
GO:0017046IPI-peptide hormone binding22682227
GO:0097689ISS-iron channel activity-
GO ID Evidence Qualifier GO_term References
GO:0002260IEA-lymphocyte homeostasis-
GO:0003158IEA-endothelium development-
GO:0006879IMP-cellular iron ion homeostasis12091367
GO:0006879TAS-cellular iron ion homeostasis-
GO:0034395IEA-regulation of transcription from RNA polymerase II promoter in response to iron-
GO:0034755IMP-iron ion transmembrane transport12091367
GO:0043066IEA-negative regulation of apoptotic process-
GO:0045944IEA-positive regulation of transcription from RNA polymerase II promoter-
GO:0060345IEA-spleen trabecula formation-
GO:0060586ISS-multicellular organismal iron ion homeostasis-
GO:1903988ISS-ferrous iron export across plasma membrane-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1315204
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-000511-8'