AutismKB 2.0

Annotation Details for ANXA1


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Basic Information Top
Gene Symbol:ANXA1 ( ANX1,LPC1 )
Gene Full Name: annexin A1
Band: 9q21.13
Quick LinksEntrez ID:301; OMIM: 151690; Uniprot ID:ANXA1_HUMAN; ENSEMBL ID: ENSG00000135046; HGNC ID: 533
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001533IDA-cornified envelope10908733
GO:0001891IEA-phagocytic cup-
GO:0005576TAS-extracellular region-
GO:0005615IDA-extracellular space17008549
GO:0005634IDA-nucleus22056994
GO:0005654IDA-nucleoplasm-
GO:0005737IDA-cytoplasm17008549
GO:0005737TAS-cytoplasm16130169
GO:0005768IDA-endosome18767904
GO:0005829IDA-cytosol-
GO:0005886IDA-plasma membrane-
GO:0005913IDA-cell-cell adherens junction25468996
GO:0005925IDA-focal adhesion21423176
GO:0009986IDA-cell surface22056994
GO:0016323IEA-basolateral plasma membrane-
GO:0016324ISS-apical plasma membrane-
GO:0016328ISS-lateral plasma membrane-
GO:0019898IDA-extrinsic component of membrane17008549
GO:0030659IEA-cytoplasmic vesicle membrane-
GO:0031232IDA-extrinsic component of external side of plasma membrane19625660
GO:0031313ISS-extrinsic component of endosome membrane-
GO:0031514ISS-motile cilium-
GO:0031901ISS-early endosome membrane-
GO:0031966IEA-mitochondrial membrane-
GO:0031982IDA-vesicle19190083
GO:0042383IEA-sarcolemma-
GO:0042629IEA-mast cell granule-
GO:0043234IEA-protein complex-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0003697IEA-single-stranded DNA binding-
GO:0003727IEA-single-stranded RNA binding-
GO:0004386IEA-helicase activity-
GO:0005102TAS-receptor binding10882119
GO:0005198IDA-structural molecule activity10908733
GO:0005509ISS-calcium ion binding-
GO:0005515IPI-protein binding21383699
GO:0005543TAS-phospholipid binding2967291
GO:0005544IDA-calcium-dependent phospholipid binding2138016
GO:0019834IDA-phospholipase A2 inhibitor activity2936963
GO:0030674IDA-protein binding, bridging10908733
GO:0033676IEA-double-stranded DNA-dependent ATPase activity-
GO:0036310IEA-annealing helicase activity-
GO:0042803IEA-protein homodimerization activity-
GO:0048306IPI-calcium-dependent protein binding15226301
GO:0098641IDA-cadherin binding involved in cell-cell adhesion25468996
GO ID Evidence Qualifier GO_term References
GO:0000733IEA-DNA strand renaturation-
GO:0001780IMP-neutrophil homeostasis21957127
GO:0002250IEA-adaptive immune response-
GO:0002548IDA-monocyte chemotaxis15187149
GO:0002685ISS-regulation of leukocyte migration-
GO:0006909ISS-phagocytosis-
GO:0006954ISS-inflammatory response-
GO:0007165TAS-signal transduction16130169
GO:0007166IEA-cell surface receptor signaling pathway-
GO:0007187IDA-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger25664854
GO:0007187IMP-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger15187149
GO:0008360IDA-regulation of cell shape15187149
GO:0010165IEA-response to X-ray-
GO:0014839IEA-myoblast migration involved in skeletal muscle regeneration-
GO:0018149IDA-peptide cross-linking10908733
GO:0030073IEA-insulin secretion-
GO:0030216IDA-keratinocyte differentiation10908733
GO:0030850IEA-prostate gland development-
GO:0031018IEA-endocrine pancreas development-
GO:0031340IDA-positive regulation of vesicle fusion2138016
GO:0031394IEA-positive regulation of prostaglandin biosynthetic process-
GO:0031532IDA-actin cytoskeleton reorganization15187149
GO:0032355IEA-response to estradiol-
GO:0032508IEA-DNA duplex unwinding-
GO:0032652ISS-regulation of interleukin-1 production-
GO:0032743IDA-positive regulation of interleukin-2 production17008549
GO:0033031IEA-positive regulation of neutrophil apoptotic process-
GO:0036292IEA-DNA rewinding-
GO:0042063IEA-gliogenesis-
GO:0042102IDA-positive regulation of T cell proliferation17008549
GO:0042493IEA-response to drug-
GO:0043066TAS-negative regulation of apoptotic process16130169
GO:0043434IEA-response to peptide hormone-
GO:0044849IEA-estrous cycle-
GO:0045087IEA-innate immune response-
GO:0045627IDA-positive regulation of T-helper 1 cell differentiation17008549
GO:0045629IDA-negative regulation of T-helper 2 cell differentiation17008549
GO:0045920IMP-negative regulation of exocytosis19625660
GO:0046632ISS-alpha-beta T cell differentiation-
GO:0046883IMP-regulation of hormone secretion19625660
GO:0050482IEA-arachidonic acid secretion-
GO:0050727ISS-regulation of inflammatory response-
GO:0070301IEA-cellular response to hydrogen peroxide-
GO:0070365IEA-hepatocyte differentiation-
GO:0070459IEA-prolactin secretion-
GO:0070555IEA-response to interleukin-1-
GO:0071385IDA-cellular response to glucocorticoid stimulus2936963
GO:0071621IDA-granulocyte chemotaxis15187149
GO:0090303IDA-positive regulation of wound healing25664854
GO:0097350IMP-neutrophil clearance21957127
GO:0098609IEA-cell-cell adhesion-
GO:1900087IEA-positive regulation of G1/S transition of mitotic cell cycle-
GO:1900138IEA-negative regulation of phospholipase A2 activity-
GO:2000483IMP-negative regulation of interleukin-8 secretion22056994
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
S100A11ANXA11121908557678 Reconstituted Complex
S100A11ANXA11067988557678 Reconstituted Complex
KRT8ANXA11100549459484 Affinity Capture-MS
KRT8ANXA11067989459484 Affinity Capture-MS
MGMTANXA111041116226712 Affinity Capture-MS
MGMTANXA110679816226712 Affinity Capture-MS
DLG3ANXA110808517353931 Affinity Capture-MS
DLG3ANXA110679817353931 Affinity Capture-MS
PPM1BANXA111149017353931 Affinity Capture-MS
PPM1BANXA110679817353931 Affinity Capture-MS
SUMO2ANXA111249719394292 Affinity Capture-MS
SUMO2ANXA110679819394292 Affinity Capture-MS
SLX1BANXA112247919596235 Affinity Capture-MS
SLX1BANXA110679819596235 Affinity Capture-MS
USPL1ANXA111550319615732 Affinity Capture-MS
USPL1ANXA110679819615732 Affinity Capture-MS
USP25ANXA111889519615732 Affinity Capture-MS
USP25ANXA110679819615732 Affinity Capture-MS
ATG4BANXA111680120562859 Affinity Capture-MS
ATG4BANXA110679820562859 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:96819
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-5274'