AutismKB 2.0

Annotation Details for SOX8


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SOX8 ( MGC24837 )
Gene Full Name: SRY (sex determining region Y)-box 8
Band: 16p13.3
Quick LinksEntrez ID:30812; OMIM: 605923; Uniprot ID:SOX8_HUMAN; ENSEMBL ID: ENSG00000005513; HGNC ID: 11203
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IC-nucleus10662550
GO:0005634IDA-nucleus18512230
GO:0005737ISS-cytoplasm-
GO:0044798IEA-nuclear transcription factor complex-
GO ID Evidence Qualifier GO_term References
GO:0000979ISS-RNA polymerase II core promoter sequence-specific DNA binding-
GO:0000981IEA-RNA polymerase II transcription factor activity, sequence-specific DNA binding-
GO:0003677NAS-DNA binding10684944
GO:0008134IEA-transcription factor binding-
GO:0046982IEA-protein heterodimerization activity-
GO ID Evidence Qualifier GO_term References
GO:0001649ISS-osteoblast differentiation-
GO:0001701ISS-in utero embryonic development-
GO:0001755ISS-neural crest cell migration-
GO:0006351IEA-transcription, DNA-templated-
GO:0007165ISS-signal transduction-
GO:0007283ISS-spermatogenesis-
GO:0007422ISS-peripheral nervous system development-
GO:0008584ISS-male gonad development-
GO:0010817ISS-regulation of hormone levels-
GO:0014015ISS-positive regulation of gliogenesis-
GO:0033690ISS-positive regulation of osteoblast proliferation-
GO:0035914IEA-skeletal muscle cell differentiation-
GO:0043066ISS-negative regulation of apoptotic process-
GO:0045165ISS-cell fate commitment-
GO:0045444ISS-fat cell differentiation-
GO:0045662ISS-negative regulation of myoblast differentiation-
GO:0045892ISS-negative regulation of transcription, DNA-templated-
GO:0045893ISS-positive regulation of transcription, DNA-templated-
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter10662550
GO:0046533IEA-negative regulation of photoreceptor cell differentiation-
GO:0048469IEA-cell maturation-
GO:0048484ISS-enteric nervous system development-
GO:0048709ISS-oligodendrocyte differentiation-
GO:0060009ISS-Sertoli cell development-
GO:0060018IEA-astrocyte fate commitment-
GO:0060041ISS-retina development in camera-type eye-
GO:0060221ISS-retinal rod cell differentiation-
GO:0060612ISS-adipose tissue development-
GO:0061138ISS-morphogenesis of a branching epithelium-
GO:0072034ISS-renal vesicle induction-
GO:0072197ISS-ureter morphogenesis-
GO:0072289ISS-metanephric nephron tubule formation-
GO:0090184ISS-positive regulation of kidney development-
GO:0090190ISS-positive regulation of branching involved in ureteric bud morphogenesis-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SOX8HOXC1111903620211142 Two-hybrid
SOX8HOXC1110946720211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:98370
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-031114-1'