AutismKB 2.0

Annotation Details for UBE2K


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Basic Information Top
Gene Symbol:UBE2K ( DKFZp564C1216,DKFZp686J24237,E2-25K,HIP2,HYPG,LIG )
Gene Full Name: ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)
Band: 4p14
Quick LinksEntrez ID:3093; OMIM: 602846; Uniprot ID:UBE2K_HUMAN; ENSEMBL ID: ENSG00000078140; HGNC ID: 4914
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IBA-nucleus-
GO:0005737IBA-cytoplasm-
GO:0005829TAS-cytosol-
GO:0032433IEA-filopodium tip-
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0004842IDA-ubiquitin-protein transferase activity20061386
GO:0005515IPI-protein binding17500595
GO:0005524IEA-ATP binding-
GO:0031625IPI-ubiquitin protein ligase binding16714285
GO:0034450IDA-ubiquitin-ubiquitin ligase activity17873885
GO ID Evidence Qualifier GO_term References
GO:0006511TAS-ubiquitin-dependent protein catabolic process8702625
GO:0010800IDA-positive regulation of peptidyl-threonine phosphorylation24882218
GO:0010994IDA-free ubiquitin chain polymerization24882218
GO:0016567TAS-protein ubiquitination-
GO:0032434IEA-regulation of proteasomal ubiquitin-dependent protein catabolic process-
GO:0035458IMP-cellular response to interferon-beta24882218
GO:0043161IBA-proteasome-mediated ubiquitin-dependent protein catabolic process-
GO:0060340IMP-positive regulation of type I interferon-mediated signaling pathway24882218
GO:0070059IEA-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-
GO:0070936IDA-protein K48-linked ubiquitination20061386
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
UBE2KHTT1093148702625 9700202 Reconstituted Complex; Two-hybrid
UBE2KHTT1093408702625 9700202 Reconstituted Complex; Two-hybrid
RNF2UBE2K11197211513855 19549727 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RNF2UBE2K10934011513855 19549727 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
DSTYKUBE2K11731317353931 Affinity Capture-MS
DSTYKUBE2K10934017353931 Affinity Capture-MS
DDX58UBE2K10934017719635 Biochemical Activity
DDX58UBE2K11712117719635 Biochemical Activity
UBE2IUBE2K11317718691969 Biochemical Activity
UBE2IUBE2K10934018691969 Biochemical Activity
RNF41UBE2K11548819549727 Two-hybrid
RNF41UBE2K10934019549727 Two-hybrid
TRAIPUBE2K11558119549727 Two-hybrid
TRAIPUBE2K10934019549727 Two-hybrid
RBCK1UBE2K11586219549727 Two-hybrid
RBCK1UBE2K10934019549727 Two-hybrid
TRIM31UBE2K11625719549727 Two-hybrid
TRIM31UBE2K10934019549727 Two-hybrid
BIRC8UBE2K10934019549727 Two-hybrid
BIRC8UBE2K12518619549727 Two-hybrid
MARCH3UBE2K12541619549727 Two-hybrid
MARCH3UBE2K10934019549727 Two-hybrid
UHRF2UBE2K12543419549727 Two-hybrid
UHRF2UBE2K10934019549727 Two-hybrid
TRIM43UBE2K12621319549727 Two-hybrid
TRIM43UBE2K10934019549727 Two-hybrid
RNF32UBE2K12662219549727 Two-hybrid
RNF32UBE2K10934019549727 Two-hybrid
DTX3LUBE2K12739219549727 Two-hybrid
DTX3LUBE2K10934019549727 Two-hybrid
DTX3UBE2K12820319549727 Two-hybrid
DTX3UBE2K10934019549727 Two-hybrid
UBOX5UBE2K11655419549727 Two-hybrid
UBOX5UBE2K10934019549727 Two-hybrid
TRIM35UBE2K11671619549727 Two-hybrid
TRIM35UBE2K10934019549727 Two-hybrid
TRIM2UBE2K11691019549727 Two-hybrid
TRIM2UBE2K10934019549727 Two-hybrid
MKRN2UBE2K11714219549727 Two-hybrid
MKRN2UBE2K10934019549727 Two-hybrid
CBLCUBE2K11715619549727 Two-hybrid
CBLCUBE2K10934019549727 Two-hybrid
RNF167UBE2K10934019549727 Two-hybrid
RNF167UBE2K11747719549727 Two-hybrid
MID1UBE2K11042719549727 Two-hybrid
MID1UBE2K10934019549727 Two-hybrid
BFARUBE2K10934019549727 Two-hybrid
BFARUBE2K11943519549727 Two-hybrid
RNF138UBE2K11954519549727 Two-hybrid
RNF138UBE2K10934019549727 Two-hybrid
TRIM34UBE2K11980919549727 Two-hybrid
TRIM34UBE2K10934019549727 Two-hybrid
RNF111UBE2K12014619549727 Two-hybrid
RNF111UBE2K10934019549727 Two-hybrid
RNF125UBE2K12028119549727 Two-hybrid
RNF125UBE2K10934019549727 Two-hybrid
RNF114UBE2K12099119549727 Two-hybrid
RNF114UBE2K10934019549727 Two-hybrid
TRIM39UBE2K10934019549727 Two-hybrid
TRIM39UBE2K12117019549727 Two-hybrid
TRIM27UBE2K11191919549727 Two-hybrid
TRIM27UBE2K10934019549727 Two-hybrid
RING1UBE2K11194719549727 Two-hybrid
RING1UBE2K10934019549727 Two-hybrid
RNF4UBE2K11197419549727 Two-hybrid
RNF4UBE2K10934019549727 Two-hybrid
RNF5UBE2K11197519549727 Two-hybrid
RNF5UBE2K10934019549727 Two-hybrid
SIAH1UBE2K11237219549727 Two-hybrid
SIAH1UBE2K10934019549727 Two-hybrid
MARCH7UBE2K12231919549727 Two-hybrid
MARCH7UBE2K10934019549727 Two-hybrid
MKRN3UBE2K11347919549727 Two-hybrid
MKRN3UBE2K10934019549727 Two-hybrid
BIRC7UBE2K12267019549727 Two-hybrid
BIRC7UBE2K10934019549727 Two-hybrid
TRAF7UBE2K10934019549727 Two-hybrid
TRAF7UBE2K12396419549727 Two-hybrid
TRIM5UBE2K12449119549727 Two-hybrid
TRIM5UBE2K10934019549727 Two-hybrid
LRSAM1UBE2K12475419549727 Two-hybrid
LRSAM1UBE2K10934019549727 Two-hybrid
RNF185UBE2K12483419549727 Two-hybrid
RNF185UBE2K10934019549727 Two-hybrid
DZIP3UBE2K10934019549727 Two-hybrid
DZIP3UBE2K11502119549727 Two-hybrid
RNF144AUBE2K10934019549727 Two-hybrid
RNF144AUBE2K11512519549727 Two-hybrid
Gene Symbol Interactant Interaction ID References Description
UBE2KHTT1304928702625 HD interacts with hE2-25K.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1858216
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-980605-9'