AutismKB 2.0

Annotation Details for ACACA


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Basic Information Top
Gene Symbol:ACACA ( ACAC,ACC,ACC1,ACCA )
Gene Full Name: acetyl-CoA carboxylase alpha
Band: 17q12
Quick LinksEntrez ID:31; OMIM: 200350; Uniprot ID:ACACA_HUMAN; ENSEMBL ID: ENSG00000132142; HGNC ID: 84
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001650IDA-fibrillar center-
GO:0005739IEA-mitochondrion-
GO:0005829IDA-cytosol-
GO:0005829ISS-cytosol-
GO:0005829TAS-cytosol-
GO:0015629IDA-actin cytoskeleton-
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0003989ISS-acetyl-CoA carboxylase activity20952656
GO:0003989TAS-acetyl-CoA carboxylase activity-
GO:0004075IEA-biotin carboxylase activity-
GO:0005515IPI-protein binding16326698
GO:0005524IEA-ATP binding-
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0001894IEA-tissue homeostasis-
GO:0006084ISS-acetyl-CoA metabolic process-
GO:0006633ISS-fatty acid biosynthetic process-
GO:0006768TAS-biotin metabolic process-
GO:0006853TAS-carnitine shuttle-
GO:0031325TAS-positive regulation of cellular metabolic process-
GO:0044268IEA-multicellular organismal protein metabolic process-
GO:0045540TAS-regulation of cholesterol biosynthetic process-
GO:0046949TAS-fatty-acyl-CoA biosynthetic process-
GO:0051289ISS-protein homotetramerization20952656
GO:0055088IEA-lipid homeostasis-
GO:0071380IEA-cellular response to prostaglandin E stimulus-
GO:2001295IEA-malonyl-CoA biosynthetic process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
BRCA1ACACA10654912360400 16326698 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
BRCA1ACACA10714012360400 16326698 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
CHGBACACA10654916169070 Two-hybrid
CHGBACACA10753916169070 Two-hybrid
PRKAA2ACACA10654920562859 Affinity Capture-MS
PRKAA2ACACA11155020562859 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
ACACArs1900101, rs2252754, rs2254914, rs2305099 Gene overview in PDGene
No data
Animal Model Top
  • MGI ID: MGI:108451
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-060526-74'