AutismKB 2.0

Annotation Details for HLX


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Basic Information Top
Gene Symbol:HLX ( HB24,HLX1 )
Gene Full Name: H2.0-like homeobox
Band: 1q41
Quick LinksEntrez ID:3142; OMIM: 142995; Uniprot ID:HLX_HUMAN; ENSEMBL ID: ENSG00000136630; HGNC ID: 4978
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IEA-nucleus-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding23455154
GO:0043565IDA-sequence-specific DNA binding9073066
GO ID Evidence Qualifier GO_term References
GO:0001889IEA-liver development-
GO:0006351IEA-transcription, DNA-templated-
GO:0006355IEA-regulation of transcription, DNA-templated-
GO:0007275TAS-multicellular organism development8094082
GO:0007519IEA-skeletal muscle tissue development-
GO:0008284IEA-positive regulation of cell proliferation-
GO:0030154IEA-cell differentiation-
GO:0045627IEA-positive regulation of T-helper 1 cell differentiation-
GO:0045629IEA-negative regulation of T-helper 2 cell differentiation-
GO:0046622IEA-positive regulation of organ growth-
GO:0048484IEA-enteric nervous system development-
GO:0048557IEA-embryonic digestive tract morphogenesis-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:96109
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018