AutismKB 2.0

Annotation Details for HOXB1


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Basic Information Top
Gene Symbol:HOXB1 ( HOX2,HOX2I,Hox-2.9,MGC116843,MGC116844,MGC116845 )
Gene Full Name: homeobox B1
Band: 17q21.32
Quick LinksEntrez ID:3211; OMIM: 142968; Uniprot ID:HXB1_HUMAN; ENSEMBL ID: ENSG00000120094; HGNC ID: 5111
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IEA-nucleus-
GO ID Evidence Qualifier GO_term References
GO:0000977IDA-RNA polymerase II regulatory region sequence-specific DNA binding9556594
GO:0000978IDA-RNA polymerase II core promoter proximal region sequence-specific DNA binding9556594
GO:0001077IDA-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding9556594
GO:0001228IDA-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding9556594
GO:0003677IDA-DNA binding10052460
GO:0019904IPI-protein domain specific binding10052460
GO ID Evidence Qualifier GO_term References
GO:0006355TAS-regulation of transcription, DNA-templated10052460
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0007275NAS-multicellular organism development10052460
GO:0007389TAS-pattern specification process10052460
GO:0009952IEA-anterior/posterior pattern specification-
GO:0021570IEA-rhombomere 4 development-
GO:0021571IEA-rhombomere 5 development-
GO:0021612IEA-facial nerve structural organization-
GO:0021754IEA-facial nucleus development-
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter9556594
GO:0048646IEA-anatomical structure formation involved in morphogenesis-
GO:0048704IEA-embryonic skeletal system morphogenesis-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
HOXB1NR3C110945112487626 Affinity Capture-Western
HOXB1NR3C110916512487626 Affinity Capture-Western
HOXB1HMGB11094518890171 Reconstituted Complex
HOXB1HMGB11093898890171 Reconstituted Complex
PBX1HOXB11094519482740 10052460 Co-crystal Structure; Reconstituted Complex
PBX1HOXB11111209482740 10052460 Co-crystal Structure; Reconstituted Complex
PAX6HOXB111111411069920 Reconstituted Complex
PAX6HOXB110945111069920 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:96182
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-980526-290'