AutismKB 2.0

Annotation Details for APBB2


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Basic Information Top
Gene Symbol:APBB2 ( DKFZp434E033,FE65L,FE65L1,MGC35575 )
Gene Full Name: amyloid beta (A4) precursor protein-binding, family B, member 2
Band: 4p14-p13
Quick LinksEntrez ID:323; OMIM: 602710; Uniprot ID:APBB2_HUMAN; ENSEMBL ID: ENSG00000163697; HGNC ID: 582
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IBA-nucleus-
GO:0005634ISS-nucleus-
GO:0005737IBA-cytoplasm-
GO:0016020NAS-membrane8855266
GO:0030027ISS-lamellipodium-
GO:0030426ISS-growth cone-
GO:0045202ISS-synapse-
GO ID Evidence Qualifier GO_term References
GO:0001540IBA-amyloid-beta binding-
GO:0001540ISS-amyloid-beta binding-
GO:0005515IPI-protein binding8855266
GO:0008134IBA-transcription factor binding-
GO:0008134ISS-transcription factor binding-
GO ID Evidence Qualifier GO_term References
GO:0001764IEA-neuron migration-
GO:0006355IBA-regulation of transcription, DNA-templated-
GO:0006355ISS-regulation of transcription, DNA-templated-
GO:0007050ISS-cell cycle arrest-
GO:0007411IEA-axon guidance-
GO:0030198IEA-extracellular matrix organization-
GO:0030308ISS-negative regulation of cell growth-
GO:0035556NAS-intracellular signal transduction8855266
GO:0043065IEA-positive regulation of apoptotic process-
GO:0043066IEA-negative regulation of apoptotic process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
APPAPBB210684814527950 Affinity Capture-Western
APPAPBB210682014527950 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
APBB2hCV11298078, hCV1154464, hCV1558549, hCV1558615, hCV1558625, hCV317172, rs10002235, rs10031715, rs10938438, rs12509038, rs12641331, rs13133980, rs4861358, rs4861368, rs6839964, rs7680971 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:108405
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-090313-73'