AutismKB 2.0

Annotation Details for APCS


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Basic Information Top
Gene Symbol:APCS ( MGC88159,PTX2,SAP )
Gene Full Name: amyloid P component, serum
Band: 1q23.2
Quick LinksEntrez ID:325; OMIM: 104770; Uniprot ID:SAMP_HUMAN; ENSEMBL ID: ENSG00000132703; HGNC ID: 584
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576NAS-extracellular region14718574
GO:0005576TAS-extracellular region-
GO:0005615IDA-extracellular space14607961
GO:0005634IDA-nucleus21630459
GO:0031012IDAcolocalizes_withextracellular matrix20551380
GO:0070062IDA-extracellular exosome19056867
GO:0072562IDA-blood microparticle22516433
GO ID Evidence Qualifier GO_term References
GO:0001849IDA-complement component C1q binding23544079
GO:0005509IDA-calcium ion binding23544079
GO:0030246IEA-carbohydrate binding-
GO:0046790IDA-virion binding23544079
GO:0051082TAS-unfolded protein binding10812074
GO ID Evidence Qualifier GO_term References
GO:0002674IC-negative regulation of acute inflammatory response14607961
GO:0006457TAS-protein folding10812074
GO:0006953TAS-acute-phase response2987268
GO:0044267TAS-cellular protein metabolic process-
GO:0044869IDA-negative regulation by host of viral exo-alpha-sialidase activity23544079
GO:0044871IDA-negative regulation by host of viral glycoprotein metabolic process23544079
GO:0045087IDA-innate immune response23544079
GO:0045656IDA-negative regulation of monocyte differentiation14607961
GO:0046597IDA-negative regulation of viral entry into host cell23544079
GO:0048525IDA-negative regulation of viral process23544079
GO:0051131TAS-chaperone-mediated protein complex assembly10972085
GO:0061045IC-negative regulation of wound healing14607961
GO:1903016IDA-negative regulation of exo-alpha-sialidase activity23544079
GO:1903019IDA-negative regulation of glycoprotein metabolic process23544079
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
C4BPAAPCS1071837592941 12100475 Affinity Capture-Western; Co-purification
C4BPAAPCS1068227592941 12100475 Affinity Capture-Western; Co-purification
APCSAPCS1068228114934 Co-crystal Structure
CRPAPCS1068228144569 Reconstituted Complex
CRPAPCS1077918144569 Reconstituted Complex
CALUAPCS10682210631319 Reconstituted Complex
CALUAPCS10726310631319 Reconstituted Complex
FCGR1AAPCS10682211359830 Reconstituted Complex
FCGR1AAPCS10850311359830 Reconstituted Complex
FCGR3AAPCS10682211359830 Reconstituted Complex
FCGR3AAPCS10850811359830 Reconstituted Complex
FCGR3BAPCS10682211359830 Reconstituted Complex
FCGR3BAPCS10850911359830 Reconstituted Complex
FN1APCS10682212100475 Affinity Capture-Western
FN1APCS10862112100475 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:98229
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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