AutismKB 2.0

Annotation Details for HPRT1


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Basic Information Top
Gene Symbol:HPRT1 ( HGPRT,HPRT )
Gene Full Name: hypoxanthine phosphoribosyltransferase 1
Band: Xq26.2-q26.3
Quick LinksEntrez ID:3251; OMIM: 308000; Uniprot ID:HPRT_HUMAN; ENSEMBL ID: ENSG00000165704; HGNC ID: 5157
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm6300847
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0070062IDA-extracellular exosome20458337
GO ID Evidence Qualifier GO_term References
GO:0000166IEA-nucleotide binding-
GO:0000287IDA-magnesium ion binding10360366
GO:0004422EXP-hypoxanthine phosphoribosyltransferase activity659426
GO:0004422IDA-hypoxanthine phosphoribosyltransferase activity6300847
GO:0005515IPI-protein binding16189514
GO:0042802IPI-identical protein binding25416956
GO:0042803IPI-protein homodimerization activity8044844
GO:0052657IDA-guanine phosphoribosyltransferase activity19527031
GO ID Evidence Qualifier GO_term References
GO:0001975IEA-response to amphetamine-
GO:0006164IMP-purine nucleotide biosynthetic process9824441
GO:0006166IMP-purine ribonucleoside salvage9824441
GO:0006168IEA-adenine salvage-
GO:0006178IDA-guanine salvage19527031
GO:0007625IEA-grooming behavior-
GO:0007626IEA-locomotory behavior-
GO:0019835IEA-cytolysis-
GO:0021756IEA-striatum development-
GO:0021895IEA-cerebral cortex neuron differentiation-
GO:0021954IEA-central nervous system neuron development-
GO:0032264IEA-IMP salvage-
GO:0042417IEA-dopamine metabolic process-
GO:0043101TAS-purine-containing compound salvage-
GO:0043103IDA-hypoxanthine salvage19527031
GO:0045964IMP-positive regulation of dopamine metabolic process8643611
GO:0046038IDA-GMP catabolic process19527031
GO:0046040IDA-IMP metabolic process19527031
GO:0046100IMP-hypoxanthine metabolic process9824441
GO:0046651IEA-lymphocyte proliferation-
GO:0048813IEA-dendrite morphogenesis-
GO:0051289IDA-protein homotetramerization9521733
GO:0051289IPI-protein homotetramerization15990111
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
HPRT1FANCA10948814499622 Two-hybrid
HPRT1FANCA10847214499622 Two-hybrid
WDYHV1HPRT110948816189514 Two-hybrid
WDYHV1HPRT112040516189514 Two-hybrid
PRTFDC1HPRT110948816189514 Two-hybrid
PRTFDC1HPRT112127616189514 Two-hybrid
EIF1BHPRT111557817353931 Affinity Capture-MS
EIF1BHPRT110948817353931 Affinity Capture-MS
HUS1HPRT110948817353931 Affinity Capture-MS
HUS1HPRT110959617353931 Affinity Capture-MS
MCCHPRT110948817353931 Affinity Capture-MS
MCCHPRT111033317353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:96217
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-1918'