AutismKB 2.0

Annotation Details for PRMT2


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Basic Information Top
Gene Symbol:PRMT2 ( HRMT1L1,MGC111373 )
Gene Full Name: protein arginine methyltransferase 2
Band: 21q22.3
Quick LinksEntrez ID:3275; OMIM: 601961; Uniprot ID:ANM2_HUMAN; ENSEMBL ID: ENSG00000160310; HGNC ID: 5186
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus11513728
GO:0005654IDA-nucleoplasm-
GO:0005730IEA-nucleolus-
GO:0005737IDA-cytoplasm11513728
GO:0005829IDA-cytosol17587566
GO:0035189ISScolocalizes_withRb-E2F complex-
GO ID Evidence Qualifier GO_term References
GO:0003713IDA-transcription coactivator activity12039952
GO:0004871TAS-signal transducer activity9545638
GO:0005515IPI-protein binding11513728
GO:0008469ISS-histone-arginine N-methyltransferase activity-
GO:0016274ISS-protein-arginine N-methyltransferase activity-
GO:0030331IDA-estrogen receptor binding17587566
GO:0030331IPI-estrogen receptor binding12039952
GO:0033142IPI-progesterone receptor binding12039952
GO:0042054IDA-histone methyltransferase activity19405910
GO:0042803IPI-protein homodimerization activity12039952
GO:0042974IPI-retinoic acid receptor binding12039952
GO:0042975IPI-peroxisome proliferator activated receptor binding12039952
GO:0046966IPI-thyroid hormone receptor binding12039952
GO:0050681IPI-androgen receptor binding17587566
GO ID Evidence Qualifier GO_term References
GO:0006479TAS-protein methylation9545638
GO:0007165TAS-signal transduction9545638
GO:0016571IDA-histone methylation19405910
GO:0016571ISS-histone methylation-
GO:0032088IDA-negative regulation of NF-kappaB transcription factor activity16648481
GO:0034969IEA-histone arginine methylation-
GO:0035246IEA-peptidyl-arginine N-methylation-
GO:0043065IGI-positive regulation of apoptotic process16648481
GO:0045892IDA-negative regulation of transcription, DNA-templated16648481
GO:0045893IDA-positive regulation of transcription, DNA-templated12039952
GO:0048588ISS-developmental cell growth-
GO:0060765IDA-regulation of androgen receptor signaling pathway17587566
GO:2000134ISS-negative regulation of G1/S transition of mitotic cell cycle-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PRMT2ESR110951112039952 Affinity Capture-Western; Reconstituted Complex
PRMT2ESR110840312039952 Affinity Capture-Western; Reconstituted Complex
HNRNPUL1PRMT211628111513728 Affinity Capture-Western; Two-hybrid
HNRNPUL1PRMT210951111513728 Affinity Capture-Western; Two-hybrid
BAT2PRMT210951114667819 Two-hybrid
BAT2PRMT211364614667819 Two-hybrid
DMRTB1PRMT210951116189514 Two-hybrid
DMRTB1PRMT212201216189514 Two-hybrid
CPSF7PRMT210951116189514 Two-hybrid
CPSF7PRMT212295716189514 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1316652
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-041104-1'