AutismKB 2.0

Annotation Details for HSPA6


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Basic Information Top
Gene Symbol:HSPA6 ( - )
Gene Full Name: heat shock 70kDa protein 6 (HSP70B')
Band: 1q23.3
Quick LinksEntrez ID:3310; OMIM: 140555; Uniprot ID:HSP76_HUMAN; ENSEMBL ID: ENSG00000173110; HGNC ID: 5239
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005737IDA-cytoplasm24061851
GO:0005814IDA-centriole24061851
GO:0005829IDA-cytosol21231916
GO:0008180IDAcolocalizes_withCOP9 signalosome18850735
GO:0034774TAS-secretory granule lumen-
GO:0070062IDA-extracellular exosome19199708
GO:0072562IDA-blood microparticle22516433
GO:1904813TAS-ficolin-1-rich granule lumen-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding21044950
GO:0005524IEA-ATP binding-
GO:0019899IPI-enzyme binding23921388
GO:0031072IPI-heat shock protein binding21231916
GO:0042623IDA-ATPase activity, coupled21231916
GO:0051082IDA-unfolded protein binding21231916
GO ID Evidence Qualifier GO_term References
GO:0006986TAS-response to unfolded protein2327978
GO:0034605IDA-cellular response to heat24061851
GO:0034605IMP-cellular response to heat21597468
GO:0042026IDA-protein refolding21231916
GO:0043312TAS-neutrophil degranulation-
GO:0070370IMPNOTcellular heat acclimation21231916
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
HSPA6CDK910745917643375 Affinity Capture-MS
HSPA6CDK910954217643375 Affinity Capture-MS
RFWD2HSPA612213616497536 Affinity Capture-MS
RFWD2HSPA610954216497536 Affinity Capture-MS
MEPCEHSPA612112217643375 Affinity Capture-MS
MEPCEHSPA610954217643375 Affinity Capture-MS
RPAP3HSPA612278317643375 Affinity Capture-MS
RPAP3HSPA610954217643375 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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