Gene Symbol:	HTR1B ( 5-HT1B,5-HT1DB,HTR1D2,HTR1DB,S12 )
Gene Full Name:	5-hydroxytryptamine (serotonin) receptor 1B
Band:	6q14.1
Quick Links	Entrez ID:3351; OMIM: 182131; Uniprot ID:5HT1B_HUMAN; ENSEMBL ID: ENSG00000135312; HGNC ID: 5287
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0005737	IEA	-	cytoplasm	-
GO:0005886	IDA	-	plasma membrane	-
GO:0005886	TAS	-	plasma membrane	-
GO:0005887	IMP	-	integral component of plasma membrane	1315531

GO ID	Evidence	Qualifier	GO_term	References
GO:0004993	IDA	-	G-protein coupled serotonin receptor activity	1315531
GO:0005515	IPI	-	protein binding	25416956
GO:0008144	IEA	-	drug binding	-
GO:0030594	IBA	-	neurotransmitter receptor activity	-
GO:0051378	IEA	-	serotonin binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0002031	IEA	-	G-protein coupled receptor internalization	-
GO:0007187	TAS	-	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	1559993
GO:0007198	IDA	-	adenylate cyclase-inhibiting serotonin receptor signaling pathway	1315531
GO:0007205	IEA	-	protein kinase C-activating G-protein coupled receptor signaling pathway	-
GO:0007268	IEA	-	chemical synaptic transmission	-
GO:0014059	IEA	-	regulation of dopamine secretion	-
GO:0014063	ISS	-	negative regulation of serotonin secretion	-
GO:0030818	IDA	-	negative regulation of cAMP biosynthetic process	8882600
GO:0032229	IEA	-	negative regulation of synaptic transmission, GABAergic	-
GO:0035690	IDA	-	cellular response to drug	1315531
GO:0042220	IEA	-	response to cocaine	-
GO:0042310	IEA	-	vasoconstriction	-
GO:0042756	IEA	-	drinking behavior	-
GO:0045471	IEA	-	response to ethanol	-
GO:0046849	IEA	-	bone remodeling	-
GO:0050795	IEA	-	regulation of behavior	-
GO:0051385	IEA	-	response to mineralocorticoid	-
GO:0051967	IEA	-	negative regulation of synaptic transmission, glutamatergic	-
GO:0071312	IDA	-	cellular response to alkaloid	1315531
GO:0071502	IEA	-	cellular response to temperature stimulus	-
GO:1904707	IMP	-	positive regulation of vascular smooth muscle cell proliferation	25871906

Gene Symbol	Interactant	Interaction ID	References	Description
HTR1D	HTR1B	109583	11854302	Affinity Capture-Western
HTR1D	HTR1B	109584	11854302	Affinity Capture-Western
GSTK1	HTR1B	131875	17353931	Affinity Capture-MS
GSTK1	HTR1B	109583	17353931	Affinity Capture-MS
NME2	HTR1B	109583	17353931	Affinity Capture-MS
NME2	HTR1B	110895	17353931	Affinity Capture-MS

AutismKB 2.0

Annotation Details for HTR1B