AutismKB 2.0

Annotation Details for APOA4


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Basic Information Top
Gene Symbol:APOA4 ( MGC142154,MGC142156 )
Gene Full Name: apolipoprotein A-IV
Band: 11q23.3
Quick LinksEntrez ID:337; OMIM: 107690; Uniprot ID:; ENSEMBL ID: ENSG00000110244; HGNC ID: 602
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576NAS-extracellular region14718574
GO:0005576TAS-extracellular region-
GO:0005615IDA-extracellular space1935934
GO:0005769TAS-early endosome-
GO:0005788TAS-endoplasmic reticulum lumen-
GO:0005829TAS-cytosol-
GO:0009986IDAcolocalizes_withcell surface1935934
GO:0034361IDA-very-low-density lipoprotein particle3095477
GO:0034364IDA-high-density lipoprotein particle3095477
GO:0042627IDA-chylomicron3095477
GO:0070062IDA-extracellular exosome23376485
GO:0072562IDA-blood microparticle22516433
GO ID Evidence Qualifier GO_term References
GO:0005319TAS-lipid transporter activity3080432
GO:0005507IDA-copper ion binding16945374
GO:0005515IPI-protein binding24311788
GO:0008289IMP-lipid binding16159879
GO:0015485IBA-cholesterol binding-
GO:0016209IDA-antioxidant activity16945374
GO:0017127IDA-cholesterol transporter activity1935934
GO:0031210IDA-phosphatidylcholine binding1935934
GO:0042803IDA-protein homodimerization activity1935934
GO:0060228IDA-phosphatidylcholine-sterol O-acyltransferase activator activity1935934
GO ID Evidence Qualifier GO_term References
GO:0001523TAS-retinoid metabolic process-
GO:0002227IDA-innate immune response in mucosa15254593
GO:0006695IBA-cholesterol biosynthetic process-
GO:0006869IDA-lipid transport1935934
GO:0006982IDA-response to lipid hydroperoxide16945374
GO:0007159IDA-leukocyte cell-cell adhesion15254593
GO:0008203IDA-cholesterol metabolic process1935934
GO:0010873IDA-positive regulation of cholesterol esterification1935934
GO:0010898IDA-positive regulation of triglyceride catabolic process2307668
GO:0019430IDA-removal of superoxide radicals16945374
GO:0030300IBA-regulation of intestinal cholesterol absorption-
GO:0031102IBA-neuron projection regeneration-
GO:0032374IDA-regulation of cholesterol transport11940599
GO:0033344IDA-cholesterol efflux1935934
GO:0033700IDA-phospholipid efflux11162594
GO:0034371IC-chylomicron remodeling2307668
GO:0034371TAS-chylomicron remodeling-
GO:0034372IDA-very-low-density lipoprotein particle remodeling2307668
GO:0034375IC-high-density lipoprotein particle remodeling1935934
GO:0034378TAS-chylomicron assembly16159879
GO:0034380IBA-high-density lipoprotein particle assembly-
GO:0034445IDA-negative regulation of plasma lipoprotein oxidation16945374
GO:0035634IEA-response to stilbenoid-
GO:0042157IEA-lipoprotein metabolic process-
GO:0042632IDA-cholesterol homeostasis1935934
GO:0042744IDA-hydrogen peroxide catabolic process16945374
GO:0043691IDA-reverse cholesterol transport3095477
GO:0044240IDA-multicellular organismal lipid catabolic process3095477
GO:0044267TAS-cellular protein metabolic process-
GO:0045723IDA-positive regulation of fatty acid biosynthetic process2307668
GO:0046470IDA-phosphatidylcholine metabolic process1935934
GO:0051006IDA-positive regulation of lipoprotein lipase activity2307668
GO:0055088IDA-lipid homeostasis3095477
GO:0065005IMP-protein-lipid complex assembly16159879
GO:0070328IBA-triglyceride homeostasis-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GPLD1APOA410908311254757 Affinity Capture-Western; Reconstituted Complex
GPLD1APOA410683411254757 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
APOA4H360Q, rs5104 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:88051
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-1263'