AutismKB 2.0

Annotation Details for ID2


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Basic Information Top
Gene Symbol:ID2 ( GIG8,ID2A,ID2H,MGC26389,bHLHb26 )
Gene Full Name: inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
Band: 2p25.1
Quick LinksEntrez ID:3398; OMIM: 600386; Uniprot ID:ID2_HUMAN; ENSEMBL ID: ENSG00000115738; HGNC ID: 5361
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus16311606
GO:0005737IDA-cytoplasm20861012
GO:0005737IDAcolocalizes_withcytoplasm16311606
GO:0005829IDA-cytosol16311606
GO:0043234ISS-protein complex-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding10915743
GO:0044325IPI-ion channel binding16311606
GO:0046983IEA-protein dimerization activity-
GO ID Evidence Qualifier GO_term References
GO:0006351IEA-transcription, DNA-templated-
GO:0007275TAS-multicellular organism development1741406
GO:0010628ISS-positive regulation of gene expression-
GO:0010629ISS-negative regulation of gene expression-
GO:0019216ISS-regulation of lipid metabolic process-
GO:0032922ISS-circadian regulation of gene expression-
GO:0033598ISS-mammary gland epithelial cell proliferation-
GO:0042752ISS-regulation of circadian rhythm-
GO:0043153ISS-entrainment of circadian clock by photoperiod-
GO:0043433IDA-negative regulation of sequence-specific DNA binding transcription factor activity14627819
GO:0045475ISS-locomotor rhythm-
GO:0045665ISS-negative regulation of neuron differentiation-
GO:0045777ISS-positive regulation of blood pressure-
GO:0045892IEA-negative regulation of transcription, DNA-templated-
GO:0045893ISS-positive regulation of transcription, DNA-templated-
GO:0048557ISS-embryonic digestive tract morphogenesis-
GO:0048661ISS-positive regulation of smooth muscle cell proliferation-
GO:0048663ISS-neuron fate commitment-
GO:0060749ISS-mammary gland alveolus development-
GO:0061030ISS-epithelial cell differentiation involved in mammary gland alveolus development-
GO:0061031ISS-endodermal digestive tract morphogenesis-
GO:0071158ISS-positive regulation of cell cycle arrest-
GO:0071931IC-positive regulation of transcription involved in G1/S transition of mitotic cell cycle16311606
GO:0090398ISS-cellular senescence-
GO:2000045IMP-regulation of G1/S transition of mitotic cell cycle16311606
GO:2000178ISS-negative regulation of neural precursor cell proliferation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ID2ADD110663110585876 Reconstituted Complex
ID2ADD110962410585876 Reconstituted Complex
ID2NKX2-510786416556596 Affinity Capture-Western
ID2NKX2-510962416556596 Affinity Capture-Western
ID2E2F410820616776654 Affinity Capture-Western
ID2E2F410962416776654 Affinity Capture-Western
ID2GATA410889616556596 Affinity Capture-Western; Reconstituted Complex
ID2GATA410962416556596 Affinity Capture-Western; Reconstituted Complex
TCF4ID21127878576241 9242638 9584154 Two-hybrid
TCF4ID21096248576241 9242638 9584154 Two-hybrid
MYF6ID21107039242638 Affinity Capture-Western
MYF6ID21096249242638 Affinity Capture-Western
MYOD1ID21107379242638 Affinity Capture-Western; Two-hybrid
MYOD1ID21096249242638 Affinity Capture-Western; Two-hybrid
ELSPBP1ID21220609242638 Affinity Capture-Western; Two-hybrid
ELSPBP1ID21096249242638 Affinity Capture-Western; Two-hybrid
MYF5ID21107029242638 Two-hybrid
MYF5ID21096249242638 Two-hybrid
TCF3ID21127919242638 Two-hybrid
TCF3ID21096249242638 Two-hybrid
TCF12ID21127989242638 Two-hybrid
TCF12ID21096249242638 Two-hybrid
BCAR1ID211493410502414 Affinity Capture-Western
BCAR1ID210962410502414 Affinity Capture-Western
NEDD9ID211081610502414 Affinity Capture-Western; Two-hybrid
NEDD9ID210962410502414 Affinity Capture-Western; Two-hybrid
MSCID211466911560778 Two-hybrid
MSCID210962411560778 Two-hybrid
C1orf103ID212090516169070 Two-hybrid
C1orf103ID210962416169070 Two-hybrid
C7orf64ID212385516169070 Two-hybrid
C7orf64ID210962416169070 Two-hybrid
UNC119ID211454816169070 Two-hybrid
UNC119ID210962416169070 Two-hybrid
SIN3AID211743916776654 Affinity Capture-Western
SIN3AID210962416776654 Affinity Capture-Western
RBL2ID211186916776654 Affinity Capture-Western
RBL2ID210962416776654 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:96397
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-020910-1'