AutismKB 2.0

Annotation Details for ID3


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Basic Information Top
Gene Symbol:ID3 ( HEIR-1,bHLHb25 )
Gene Full Name: inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
Band: 1p36.12
Quick LinksEntrez ID:3399; OMIM: 600277; Uniprot ID:ID3_HUMAN; ENSEMBL ID: ENSG00000117318; HGNC ID: 5362
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IEA-nucleus-
GO:0005737IEA-cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0003700IEA-transcription factor activity, sequence-specific DNA binding-
GO:0003714TAS-transcription corepressor activity8437843
GO:0005515IPI-protein binding20861012
GO:0008134IEA-transcription factor binding-
GO:0019904IEA-protein domain specific binding-
GO:0046983IEA-protein dimerization activity-
GO:1901707IEA-leptomycin B binding-
GO ID Evidence Qualifier GO_term References
GO:0000122IEA-negative regulation of transcription from RNA polymerase II promoter-
GO:0001656IEA-metanephros development-
GO:0006275IEA-regulation of DNA replication-
GO:0006351IEA-transcription, DNA-templated-
GO:0007275TAS-multicellular organism development1628620
GO:0007417IEA-central nervous system development-
GO:0007507IEA-heart development-
GO:0007517IEA-muscle organ development-
GO:0007623IEA-circadian rhythm-
GO:0009611IEA-response to wounding-
GO:0030182IEA-neuron differentiation-
GO:0030855IEA-epithelial cell differentiation-
GO:0030903IEA-notochord development-
GO:0042476IEA-odontogenesis-
GO:0043065IEA-positive regulation of apoptotic process-
GO:0043433IDA-negative regulation of sequence-specific DNA binding transcription factor activity14627819
GO:0045662IEA-negative regulation of myoblast differentiation-
GO:0045668IEA-negative regulation of osteoblast differentiation-
GO:0045892IDA-negative regulation of transcription, DNA-templated14627819
GO:0051726IEA-regulation of cell cycle-
GO:0072750IEA-cellular response to leptomycin B-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ID3ADD110663110585876 Reconstituted Complex
ID3ADD110962510585876 Reconstituted Complex
ID3NKX2-510786416556596 Affinity Capture-Western
ID3NKX2-510962516556596 Affinity Capture-Western
ID3E2F410820620211142 Two-hybrid
ID3E2F410962520211142 Two-hybrid
ID3GATA410889616556596 Affinity Capture-Western; Reconstituted Complex
ID3GATA410962516556596 Affinity Capture-Western; Reconstituted Complex
TCF4ID31127878999959 9242638 Reconstituted Complex; Two-hybrid
TCF4ID31096258999959 9242638 Reconstituted Complex; Two-hybrid
MYF6ID31107039242638 Affinity Capture-Western
MYF6ID31096259242638 Affinity Capture-Western
MYOD1ID31107379242638 Affinity Capture-Western
MYOD1ID31096259242638 Affinity Capture-Western
ELSPBP1ID31220609242638 Affinity Capture-Western; Two-hybrid
ELSPBP1ID31096259242638 Affinity Capture-Western; Two-hybrid
TCF3ID31127919242638 9525934 Reconstituted Complex; Two-hybrid
TCF3ID31096259242638 9525934 Reconstituted Complex; Two-hybrid
MYF5ID31107029242638 Two-hybrid
MYF5ID31096259242638 Two-hybrid
TCF12ID31096259242638 Two-hybrid
TCF12ID31127989242638 Two-hybrid
PAX5ID311111312054881 Affinity Capture-Western
PAX5ID310962512054881 Affinity Capture-Western
PRDM14ID312202520211142 Two-hybrid
PRDM14ID310962520211142 Two-hybrid
IKBKGID311408920211142 Two-hybrid
IKBKGID310962520211142 Two-hybrid
SAP30ID310962520211142 Two-hybrid
SAP30ID311434620211142 Two-hybrid
CBFA2T2ID310962520211142 Two-hybrid
CBFA2T2ID311458620211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:96398
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-020515-1'