AutismKB 2.0

Annotation Details for IFIT1


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Basic Information Top
Gene Symbol:IFIT1 ( C56,G10P1,GARG-16,IFI-56,IFI-56K,IFI56,IFIT-1,IFNAI1,ISG56,RNM561 )
Gene Full Name: interferon-induced protein with tetratricopeptide repeats 1
Band: 10q23.31
Quick LinksEntrez ID:3434; OMIM: 147690; Uniprot ID:IFIT1_HUMAN; ENSEMBL ID: ENSG00000185745; HGNC ID: 5407
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm19008854
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0043657IEA-host cell-
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding21642987
GO:0005515IPI-protein binding16189514
GO ID Evidence Qualifier GO_term References
GO:0009615IDA-response to virus19416887
GO:0009615IMP-response to virus21642987
GO:0019060IDA-intracellular transport of viral protein in host cell19008854
GO:0032091IDA-negative regulation of protein binding19416887
GO:0045070IDA-positive regulation of viral genome replication19416887
GO:0045071IMP-negative regulation of viral genome replication19008854
GO:0050689IDA-negative regulation of defense response to virus by host19416887
GO:0051097IDA-negative regulation of helicase activity19008854
GO:0051607IEA-defense response to virus-
GO:0060337TAS-type I interferon signaling pathway-
GO:0071357IDA-cellular response to type I interferon19008854
GO:0071360IDA-cellular response to exogenous dsRNA19008854
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
EIF3EIFIT110965910644362 Affinity Capture-Western
EIF3EIFIT110985710644362 Affinity Capture-Western
IFIT3IFIT110965916189514 Two-hybrid
IFIT3IFIT110966016189514 Two-hybrid
SAP25IFIT194101816449650 Affinity Capture-MS
SAP25IFIT110965916449650 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:99450
  • Data Attributes: MGI curated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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