AutismKB 2.0

Annotation Details for IFIT3


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Basic Information Top
Gene Symbol:IFIT3 ( CIG-49,GARG-49,IFI60,IFIT4,IRG2,ISG60,RIG-G )
Gene Full Name: interferon-induced protein with tetratricopeptide repeats 3
Band: 10q23.31
Quick LinksEntrez ID:3437; OMIM: 604650; Uniprot ID:IFIT3_HUMAN; ENSEMBL ID: ENSG00000119917; HGNC ID: 5411
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm17050680
GO:0005739IDA-mitochondrion21813773
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0003674ND-molecular_function-
GO:0005515IPI-protein binding16189514
GO:0042802IPI-identical protein binding16189514
GO ID Evidence Qualifier GO_term References
GO:0008285IDA-negative regulation of cell proliferation17050680
GO:0009615IMP-response to virus21642987
GO:0035457IEA-cellular response to interferon-alpha-
GO:0043066IDA-negative regulation of apoptotic process21190939
GO:0051607IBA-defense response to virus-
GO:0060337TAS-type I interferon signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
IFIT3FANCA10966014499622 Two-hybrid
IFIT3FANCA10847214499622 Two-hybrid
IFIT3IFIT210965816189514 Two-hybrid
IFIT3IFIT210966016189514 Two-hybrid
IFIT3IFIT110965916189514 Two-hybrid
IFIT3IFIT110966016189514 Two-hybrid
CCDC67IFIT310966016189514 Two-hybrid
CCDC67IFIT312774616189514 Two-hybrid
IFIT3IFIT310966016189514 Two-hybrid
SAP25IFIT394101816449650 Affinity Capture-MS
SAP25IFIT310966016449650 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1101055
  • Data Attributes: HomoloGene calculated
No data
No data

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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