AutismKB 2.0

Annotation Details for IGF2


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Basic Information Top
Gene Symbol:IGF2 ( C11orf43,FLJ22066,FLJ44734,IGF-II,PP9974 )
Gene Full Name: insulin-like growth factor 2 (somatomedin A)
Band: 11p15.5
Quick LinksEntrez ID:3481; OMIM: 147470; Uniprot ID:IGF2_HUMAN; ENSEMBL ID: ENSG00000129965,ENSG00000167244; HGNC ID: 5466
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005615IEA-extracellular space-
GO:0005886TAS-plasma membrane-
GO:0031093TAS-platelet alpha granule lumen-
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0005158IPI-insulin receptor binding12138094
GO:0005159IMP-insulin-like growth factor receptor binding2967174
GO:0005179IEA-hormone activity-
GO:0005515IPI-protein binding10611375
GO:0008083IDA-growth factor activity11500939
GO:0030546ISS-receptor activator activity-
GO:0043539ISS-protein serine/threonine kinase activator activity-
GO ID Evidence Qualifier GO_term References
GO:0001501TAS-skeletal system development8298652
GO:0001503IEA-ossification-
GO:0001934ISS-positive regulation of protein phosphorylation-
GO:0002576TAS-platelet degranulation-
GO:0006006IEA-glucose metabolic process-
GO:0006349TAS-regulation of gene expression by genetic imprinting8968759
GO:0006355NAS-regulation of transcription, DNA-templated12881524
GO:0007275TAS-multicellular organism development6382022
GO:0008284IC-positive regulation of cell proliferation11500939
GO:0008286TAS-insulin receptor signaling pathway1845984
GO:0038028ISS-insulin receptor signaling pathway via phosphatidylinositol 3-kinase-
GO:0042104IDA-positive regulation of activated T cell proliferation15694994
GO:0043085ISS-positive regulation of catalytic activity-
GO:0043410IDA-positive regulation of MAPK cascade11500939
GO:0044267TAS-cellular protein metabolic process-
GO:0045725ISS-positive regulation of glycogen biosynthetic process-
GO:0045840IDA-positive regulation of mitotic nuclear division11500939
GO:0046628IDA-positive regulation of insulin receptor signaling pathway11500939
GO:0050731ISS-positive regulation of peptidyl-tyrosine phosphorylation-
GO:0051781IEA-positive regulation of cell division-
GO:0051897IDA-positive regulation of protein kinase B signaling11500939
GO:0071902IEA-positive regulation of protein serine/threonine kinase activity-
GO:2000273IEA-positive regulation of receptor activity-
GO:2000467ISS-positive regulation of glycogen (starch) synthase activity-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
IGF2IDE1097021733942 Reconstituted Complex
IGF2IDE1096421733942 Reconstituted Complex
IGFBP6IGF21097027683646 Reconstituted Complex
IGFBP6IGF21097107683646 Reconstituted Complex
IGFBP7IGF21097028939990 Reconstituted Complex
IGFBP7IGF21097118939990 Reconstituted Complex
IGFBP3IGF21097029446566 9497324 11600567 11749962 Reconstituted Complex
IGFBP3IGF21097079446566 9497324 11600567 11749962 Reconstituted Complex
IGFBP5IGF21097029497324 Reconstituted Complex
IGFBP5IGF21097099497324 Reconstituted Complex
IGFBP4IGF21097029722589 Reconstituted Complex
IGFBP4IGF21097089722589 Reconstituted Complex
NOVIGF211091810084601 Reconstituted Complex
NOVIGF210970210084601 Reconstituted Complex
VTNIGF211328710342887 Reconstituted Complex
VTNIGF210970210342887 Reconstituted Complex
IGFBP1IGF210970510810289 Reconstituted Complex
IGFBP1IGF210970210810289 Reconstituted Complex
TFIGF211287611749962 Reconstituted Complex
TFIGF210970211749962 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
IGF2rs680 Gene overview in PDGene
Gene Symbol Poly Names Gene overview in SZGene
IGF2rs4320932, rs7924316 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:96434
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-2935'