AutismKB 2.0

Annotation Details for IGF2R


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:IGF2R ( CD222,CIMPR,M6P-R,MPR1,MPRI )
Gene Full Name: insulin-like growth factor 2 receptor
Band: 6q25.3
Quick LinksEntrez ID:3482; OMIM: 147280; Uniprot ID:MPRI_HUMAN; ENSEMBL ID: ENSG00000197081; HGNC ID: 5467
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005615IEA-extracellular space-
GO:0005641IEA-nuclear envelope lumen-
GO:0005765IEA-lysosomal membrane-
GO:0005768IDA-endosome15078902
GO:0005769IMP-early endosome17959629
GO:0005770IDA-late endosome22456507
GO:0005794IDA-Golgi apparatus-
GO:0005802IMP-trans-Golgi network17959629
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane10799489
GO:0005925IDA-focal adhesion21423176
GO:0009986IDA-cell surface10900005
GO:0016020IDA-membrane19946888
GO:0030118IEA-clathrin coat-
GO:0030133TAS-transport vesicle-
GO:0030139IDA-endocytic vesicle10900005
GO:0030140IDA-trans-Golgi network transport vesicle15078902
GO:0030665TAS-clathrin-coated vesicle membrane-
GO:0030667TAS-secretory granule membrane-
GO:0032588TAS-trans-Golgi network membrane-
GO:0048471IEA-perinuclear region of cytoplasm-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0001948IDA-glycoprotein binding10900005
GO:0001965IEA-G-protein alpha-subunit binding-
GO:0001972IEA-retinoic acid binding-
GO:0004872TAS-receptor activity7753549
GO:0004930IEA-G-protein coupled receptor activity-
GO:0005010TAS-insulin-like growth factor-activated receptor activity10799489
GO:0005215IEA-transporter activity-
GO:0005515IPI-protein binding10900005
GO:0005537IEA-mannose binding-
GO:0019899IEA-enzyme binding-
GO:0031995IEA-insulin-like growth factor II binding-
GO:0042802IPI-identical protein binding22681933
GO:0051219IDA-phosphoprotein binding10900005
GO ID Evidence Qualifier GO_term References
GO:0001889IEA-liver development-
GO:0006898TAS-receptor-mediated endocytosis10799489
GO:0007165TAS-signal transduction7753549
GO:0007186IEA-G-protein coupled receptor signaling pathway-
GO:0007283IEA-spermatogenesis-
GO:0009791IEA-post-embryonic development-
GO:0031100IEA-animal organ regeneration-
GO:0032526IEA-response to retinoic acid-
GO:0043065IEA-positive regulation of apoptotic process-
GO:0043312TAS-neutrophil degranulation-
GO:0048009IEA-insulin-like growth factor receptor signaling pathway-
GO:0061024TAS-membrane organization-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PLAURIGF2R1097039566979 Reconstituted Complex
PLAURIGF2R1113459566979 Reconstituted Complex
PLIN3IGF2R1097039590177 10908666 Reconstituted Complex; Two-hybrid
PLIN3IGF2R1155209590177 10908666 Reconstituted Complex; Two-hybrid
CREG1IGF2R10970312934103 Reconstituted Complex
CREG1IGF2R11433212934103 Reconstituted Complex
USP50IGF2R13188419615732 Affinity Capture-MS
USP50IGF2R10970319615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:96435
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-041014-300'