Annotation Details for IGFBP4
Basic Information Top
| Gene Symbol: | IGFBP4 ( BP-4,HT29-IGFBP,IBP4,IGFBP-4 ) |
|---|---|
| Gene Full Name: | insulin-like growth factor binding protein 4 |
| Band: | 17q21.2 |
| Quick Links | Entrez ID:3487; OMIM: 146733; Uniprot ID:IBP4_HUMAN; ENSEMBL ID: ENSG00000141753; HGNC ID: 5473 |
| Relate to Another Database: | SFARIGene; denovo-db |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0005576 | TAS | - | extracellular region | - |
| GO:0005615 | IBA | - | extracellular space | - |
| GO:0005788 | TAS | - | endoplasmic reticulum lumen | - |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0005102 | TAS | - | receptor binding | 24431302 |
| GO:0031994 | IBA | - | insulin-like growth factor I binding | - |
| GO:0031995 | IBA | - | insulin-like growth factor II binding | - |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0001501 | TAS | - | skeletal system development | 1377672 |
| GO:0001558 | IEA | - | regulation of cell growth | - |
| GO:0006259 | TAS | - | DNA metabolic process | 1377672 |
| GO:0006954 | IEA | - | inflammatory response | - |
| GO:0007165 | TAS | - | signal transduction | 1377672 |
| GO:0008283 | TAS | - | cell proliferation | 1377672 |
| GO:0010906 | IEA | - | regulation of glucose metabolic process | - |
| GO:0043410 | IEA | - | positive regulation of MAPK cascade | - |
| GO:0043567 | IBA | - | regulation of insulin-like growth factor receptor signaling pathway | - |
| GO:0043568 | IEA | - | positive regulation of insulin-like growth factor receptor signaling pathway | - |
| GO:0043687 | TAS | - | post-translational protein modification | - |
| GO:0044267 | TAS | - | cellular protein metabolic process | - |
| GO:0044342 | IEA | - | type B pancreatic cell proliferation | - |
| GO:0090090 | TAS | - | negative regulation of canonical Wnt signaling pathway | 24431302 |
| Gene Symbol | Interactant | Interaction ID | References | Description |
|---|---|---|---|---|
| IGFBP4 | HK3 | 109708 | 11068878 | Reconstituted Complex; Two-hybrid |
| IGFBP4 | HK3 | 109348 | 11068878 | Reconstituted Complex; Two-hybrid |
| IGFBP4 | IGF1 | 109708 | 7683646 9722589 | Reconstituted Complex |
| IGFBP4 | IGF1 | 109700 | 7683646 9722589 | Reconstituted Complex |
| IGFBP4 | IGF2 | 109702 | 9722589 | Reconstituted Complex |
| IGFBP4 | IGF2 | 109708 | 9722589 | Reconstituted Complex |
| Gene Symbol | Interactant | Interaction ID | References | Description |
|---|---|---|---|---|
| IGFBP4 | HK2 | 171767 | 11068878 | HKII interacts with IGFBP-4. This interaction was modeled on a demonstrated interaction between rat HKII and human IGFBP-4. |
| No data |
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