AutismKB 2.0

Annotation Details for IGFBP5


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Basic Information Top
Gene Symbol:IGFBP5 ( IBP5 )
Gene Full Name: insulin-like growth factor binding protein 5
Band: 2q35
Quick LinksEntrez ID:3488; OMIM: 146734; Uniprot ID:IBP5_HUMAN; ENSEMBL ID: ENSG00000115461; HGNC ID: 5474
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576NAS-extracellular region14718574
GO:0005576TAS-extracellular region-
GO:0005788TAS-endoplasmic reticulum lumen-
GO:0016942IC-insulin-like growth factor binding protein complex10766744
GO:0042567IDA-insulin-like growth factor ternary complex9497324
GO ID Evidence Qualifier GO_term References
GO:0001968IBA-fibronectin binding-
GO:0005515IPI-protein binding15700281
GO:0031994IPI-insulin-like growth factor I binding10766744
GO:0031995IBA-insulin-like growth factor II binding-
GO ID Evidence Qualifier GO_term References
GO:0001558IEA-regulation of cell growth-
GO:0001649IEA-osteoblast differentiation-
GO:0006006IEA-glucose metabolic process-
GO:0007165NAS-signal transduction7525452
GO:0007565IEA-female pregnancy-
GO:0007568IEA-aging-
GO:0010906IEA-regulation of glucose metabolic process-
GO:0014912IDA-negative regulation of smooth muscle cell migration10766744
GO:0017148IDA-negative regulation of translation15700281
GO:0030336IDA-negative regulation of cell migration15700281
GO:0031069IEA-hair follicle morphogenesis-
GO:0035556IEA-intracellular signal transduction-
GO:0042593IEA-glucose homeostasis-
GO:0043568IEA-positive regulation of insulin-like growth factor receptor signaling pathway-
GO:0043569IDA-negative regulation of insulin-like growth factor receptor signaling pathway10766744
GO:0043687TAS-post-translational protein modification-
GO:0044267TAS-cellular protein metabolic process-
GO:0044342IEA-type B pancreatic cell proliferation-
GO:0045668IEA-negative regulation of osteoblast differentiation-
GO:0045926IEA-negative regulation of growth-
GO:0048286IEA-lung alveolus development-
GO:0048662IDA-negative regulation of smooth muscle cell proliferation10766744
GO:0051146IEA-striated muscle cell differentiation-
GO:0051897IEA-positive regulation of protein kinase B signaling-
GO:0060056IEA-mammary gland involution-
GO:0060416ISS-response to growth hormone-
GO:0071320IDA-cellular response to cAMP7559606
GO:0071407IDA-cellular response to organic cyclic compound7559606
GO:1901862IEA-negative regulation of muscle tissue development-
GO:1904205IEA-negative regulation of skeletal muscle hypertrophy-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
IGFBP5FHL210970911821401 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
IGFBP5FHL210856511821401 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
IGFBP5IGF11097099497324 Reconstituted Complex
IGFBP5IGF11097009497324 Reconstituted Complex
IGFBP5IGF21097029497324 Reconstituted Complex
IGFBP5IGF21097099497324 Reconstituted Complex
IGFBP5IGFALS1097049497324 Reconstituted Complex
IGFBP5IGFALS1097099497324 Reconstituted Complex
SERPINE1IGFBP51097099202242 Affinity Capture-Western
SERPINE1IGFBP51110919202242 Affinity Capture-Western
SPP1IGFBP511257410698186 Reconstituted Complex
SPP1IGFBP510970910698186 Reconstituted Complex
THBS1IGFBP510970910698186 Reconstituted Complex
THBS1IGFBP511291510698186 Reconstituted Complex
ADAM12IGFBP511373111095942 Biochemical Activity
ADAM12IGFBP510970911095942 Biochemical Activity
VTNIGFBP511328711751588 Reconstituted Complex
VTNIGFBP510970911751588 Reconstituted Complex
BAT3IGFBP510970916169070 Two-hybrid
BAT3IGFBP511364716169070 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:96440
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040319-2'