AutismKB 2.0

Annotation Details for IGHM


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Basic Information Top
Gene Symbol:IGHM ( AGM1,DKFZp686I15196,DKFZp686I15212,FLJ00385,MGC104996,MGC52291,MU,VH )
Gene Full Name: immunoglobulin heavy constant mu
Band: 14q32.33
Quick LinksEntrez ID:3507; OMIM: 147020; Uniprot ID:; ENSEMBL ID: ; HGNC ID: 5541
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005615IDA-extracellular space16502470
GO:0005886TAS-plasma membrane-
GO:0009897IBA-external side of plasma membrane-
GO:0009986IDA-cell surface22427638
GO:0016021IEA-integral component of membrane-
GO:0070062IDA-extracellular exosome19199708
GO:0071756IDA-pentameric IgM immunoglobulin complex21786026
GO:0071757IDA-hexameric IgM immunoglobulin complex21786026
GO:0072562IDA-blood microparticle22516433
GO ID Evidence Qualifier GO_term References
GO:0003697IDAcontributes_tosingle-stranded DNA binding21786026
GO:0003823IBA-antigen binding-
GO:0005515IPI-protein binding19214191
GO:0031210IDAcontributes_tophosphatidylcholine binding21786026
GO:0034987IDAcontributes_toimmunoglobulin receptor binding23250751
GO:0042834IDAcontributes_topeptidoglycan binding21786026
GO ID Evidence Qualifier GO_term References
GO:0002250IDA-adaptive immune response21786026
GO:0006910IBA-phagocytosis, recognition-
GO:0006911IBA-phagocytosis, engulfment-
GO:0006958IBA-complement activation, classical pathway-
GO:0019731IDA-antibacterial humoral response21786026
GO:0045087IDA-innate immune response21786026
GO:0050829IDA-defense response to Gram-negative bacterium22427638
GO:0050853IBA-B cell receptor signaling pathway-
GO:0050871IBA-positive regulation of B cell activation-
GO:0050900TAS-leukocyte migration-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CEP72IGHM12084416189514 Two-hybrid
CEP72IGHM10972716189514 Two-hybrid
SEL1LIGHM11230018314878 Affinity Capture-Western
SEL1LIGHM10972718314878 Affinity Capture-Western
SYVN1IGHM10972718314878 Affinity Capture-Western
SYVN1IGHM12408518314878 Affinity Capture-Western
BTRCIGHM11445719615732 Affinity Capture-MS
BTRCIGHM10972719615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:96448
  • Data Attributes: MGI curated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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