AutismKB 2.0

Annotation Details for IL2RB


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Basic Information Top
Gene Symbol:IL2RB ( CD122,P70-75 )
Gene Full Name: interleukin 2 receptor, beta
Band: 22q12.3
Quick LinksEntrez ID:3560; OMIM: 146710; Uniprot ID:IL2RB_HUMAN; ENSEMBL ID: ENSG00000100385; HGNC ID: 6009
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005622IEA-intracellular-
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane8514792
GO:0009897ISS-external side of plasma membrane-
GO:0016020IDA-membrane19946888
GO ID Evidence Qualifier GO_term References
GO:0004911IDA-interleukin-2 receptor activity7736574
GO:0004911TAScontributes_tointerleukin-2 receptor activity2467293
GO:0005088TAS-Ras guanyl-nucleotide exchange factor activity-
GO:0005515IPI-protein binding23104097
GO:0019976ISS-interleukin-2 binding-
GO ID Evidence Qualifier GO_term References
GO:0000165TAS-MAPK cascade-
GO:0006461TAS-protein complex assembly2467293
GO:0007165TAS-signal transduction2785715
GO:0016032IEA-viral process-
GO:0019221IDA-cytokine-mediated signaling pathway7736574
GO:0038110IEA-interleukin-2-mediated signaling pathway-
GO:0043066IDA-negative regulation of apoptotic process7736574
GO:0043547IEA-positive regulation of GTPase activity-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
IL2RBCISH10757410514520 Affinity Capture-Western
IL2RBCISH10977510514520 Affinity Capture-Western
IL2RBGRB210914210602027 Reconstituted Complex
IL2RBGRB210977510602027 Reconstituted Complex
JAK1IL2RB1099197973658 7973659 9553136 9774657 12133952 Affinity Capture-Western; Reconstituted Complex
JAK1IL2RB1097757973658 7973659 9553136 9774657 12133952 Affinity Capture-Western; Reconstituted Complex
SHC1IL2RB1097758294403 10602027 Affinity Capture-Western; Reconstituted Complex
SHC1IL2RB1123618294403 10602027 Affinity Capture-Western; Reconstituted Complex
JAK2IL2RB1099209553136 Affinity Capture-Western
JAK2IL2RB1097759553136 Affinity Capture-Western
STAT1IL2RB10977510602027 Reconstituted Complex
STAT1IL2RB11264910602027 Reconstituted Complex
STAT3IL2RB11265110602027 Reconstituted Complex
STAT3IL2RB10977510602027 Reconstituted Complex
STAT5AIL2RB11265310602027 Reconstituted Complex
STAT5AIL2RB10977510602027 Reconstituted Complex
STAT5BIL2RB11265410602027 Reconstituted Complex
STAT5BIL2RB10977510602027 Reconstituted Complex
SOCS1IL2RB11420311133764 Affinity Capture-Western
SOCS1IL2RB10977511133764 Affinity Capture-Western
SHBIL2RB11235812200137 Reconstituted Complex
SHBIL2RB10977512200137 Reconstituted Complex
GNB2L1IL2RB10977512960323 Reconstituted Complex
GNB2L1IL2RB11567112960323 Reconstituted Complex
HGSIL2RB10977518445679 Affinity Capture-Western; Reconstituted Complex
HGSIL2RB11459318445679 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
IL2RBIL2RB_2bpSTR, rs228942, rs229492, rs734139, rs743777, rs84459, rs84460, rs9286 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:96550
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-080108-2'