AutismKB 2.0

Annotation Details for IL7


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Basic Information Top
Gene Symbol:IL7 ( IL-7 )
Gene Full Name: interleukin 7
Band: 8q21.13
Quick LinksEntrez ID:3574; OMIM: 146660; Uniprot ID:IL7_HUMAN; ENSEMBL ID: ENSG00000104432; HGNC ID: 6023
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005615IEA-extracellular space-
GO ID Evidence Qualifier GO_term References
GO:0005125IEA-cytokine activity-
GO:0005139IEA-interleukin-7 receptor binding-
GO:0005515IPI-protein binding8266077
GO:0008083ISS-growth factor activity-
GO ID Evidence Qualifier GO_term References
GO:0002360IEA-T cell lineage commitment-
GO:0006959TAS-humoral immune response2643102
GO:0007267TAS-cell-cell signaling2643102
GO:0008284TAS-positive regulation of cell proliferation2643102
GO:0009887TAS-animal organ morphogenesis2643102
GO:0010468IEA-regulation of gene expression-
GO:0030890ISS-positive regulation of B cell proliferation-
GO:0043066ISS-negative regulation of apoptotic process-
GO:0043086IEA-negative regulation of catalytic activity-
GO:0045453ISS-bone resorption-
GO:0045582ISS-positive regulation of T cell differentiation-
GO:0046622IEA-positive regulation of organ growth-
GO:0048873IEA-homeostasis of number of cells within a tissue-
GO:2001240IEA-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:96561
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018