Annotation Details for IL10RA

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Basic Information Top

Gene Symbol:	IL10RA ( CDW210A,HIL-10R,IL-10R1,IL10R )
Gene Full Name:	interleukin 10 receptor, alpha
Band:	11q23.3
Quick Links	Entrez ID:3587; OMIM: 146933; Uniprot ID:I10R1_HUMAN; ENSEMBL ID: ENSG00000110324; HGNC ID: 5964
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

AlzGene, PDGene and SZGene

Gene Ontology

Cellular Component:3 results
Molecular Function:5 results
Biological Process:3 results

GO ID	Evidence	Qualifier	GO_term	References
GO:0005886	IBA	-	plasma membrane	-
GO:0005886	TAS	-	plasma membrane	-
GO:0016021	IBA	-	integral component of membrane	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0004871	TAS	-	signal transducer activity	8120391
GO:0004872	TAS	-	receptor activity	8407942
GO:0004920	IBA	-	interleukin-10 receptor activity	-
GO:0005515	IPI	-	protein binding	11485736
GO:0019969	IEA	-	interleukin-10 binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0019221	IEA	-	cytokine-mediated signaling pathway	-
GO:0032496	IEA	-	response to lipopolysaccharide	-
GO:0050807	IEA	-	regulation of synapse organization	-

Protein-Protein Interaction

BioGRID:6 results
BIND:0 results
HPRD:0 results

Gene Symbol	Interactant	Interaction ID	References	Description
IL10RA	IL10	109800	7759550 8248239 10231374 11485736 11717514	Co-crystal Structure; Co-purification; Reconstituted Complex
IL10RA	IL10	109801	7759550 8248239 10231374 11485736 11717514	Co-crystal Structure; Co-purification; Reconstituted Complex
IL10RB	IL10RA	109802	9312047	Affinity Capture-Western
IL10RB	IL10RA	109801	9312047	Affinity Capture-Western
JAK1	IL10RA	109801	12133952 12374810	Reconstituted Complex
JAK1	IL10RA	109919	12133952 12374810	Reconstituted Complex

AlzGene, PDGene and SZGene

Alz Gene:0 results
PD Gene:0 results
SZ Gene:1 results

Gene Symbol	Poly Names	Gene overview in SZGene
IL10RA	rs2229113, rs3135932	Gene overview in SZGene

Animal Model

Mouse:1 results
Fruit Fly:0 results

MGI ID: MGI:96538
Data Attributes: MGI curated and HomoloGene calculated

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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