AutismKB 2.0

Annotation Details for AQP4


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Basic Information Top
Gene Symbol:AQP4 ( HMIWC2,MGC22454,MIWC )
Gene Full Name: aquaporin 4
Band: 18q11.2
Quick LinksEntrez ID:361; OMIM: 600308; Uniprot ID:AQP4_HUMAN; ENSEMBL ID: ENSG00000171885; HGNC ID: 637
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm18392839
GO:0005886IDA-plasma membrane16814974
GO:0005886TAS-plasma membrane-
GO:0005887IBA-integral component of plasma membrane-
GO:0009897IDA-external side of plasma membrane17645239
GO:0016323IBA-basolateral plasma membrane-
GO ID Evidence Qualifier GO_term References
GO:0005372TAS-water transmembrane transporter activity7559426
GO:0005515IPI-protein binding25910212
GO:0015250EXP-water channel activity1373524
GO:0015250IBA-water channel activity-
GO ID Evidence Qualifier GO_term References
GO:0003091TAS-renal water homeostasis-
GO:0006810TAS-transport7559426
GO:0006833TAS-water transport-
GO:0034220IBA-ion transmembrane transport-
GO:0050891IEP-multicellular organismal water homeostasis16814974
GO:0071346IDA-cellular response to interferon-gamma17645239
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
AP2M1AQP410758711742978 Reconstituted Complex; Two-hybrid
AP2M1AQP410685711742978 Reconstituted Complex; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
AQP4rs162004, rs162006, rs162009, rs3763043 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:107387
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040724-152'