AutismKB 2.0

Annotation Details for IMPDH2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:IMPDH2 ( IMPD2,IMPDH-II )
Gene Full Name: IMP (inosine 5'-monophosphate) dehydrogenase 2
Band: 3p21.31
Quick LinksEntrez ID:3615; OMIM: 146691; Uniprot ID:IMDH2_HUMAN; ENSEMBL ID: ENSG00000178035; HGNC ID: 6053
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005634IDA-nucleus14766016
GO:0005737IDA-cytoplasm14766016
GO:0005778IDA-peroxisomal membrane21525035
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0016020IDA-membrane19946888
GO:0034774TAS-secretory granule lumen-
GO:0070062IDA-extracellular exosome20458337
GO:1904813TAS-ficolin-1-rich granule lumen-
GO ID Evidence Qualifier GO_term References
GO:0000166IDA-nucleotide binding14766016
GO:0003677IEA-DNA binding-
GO:0003723IEA-RNA binding-
GO:0003938EXP-IMP dehydrogenase activity7763314
GO:0003938IBA-IMP dehydrogenase activity-
GO:0005515IPI-protein binding25416956
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0006177IEA-GMP biosynthetic process-
GO:0006183IBA-GTP biosynthetic process-
GO:0009168TAS-purine ribonucleoside monophosphate biosynthetic process-
GO:0043312TAS-neutrophil degranulation-
GO:0046651IEA-lymphocyte proliferation-
GO:0051289IEA-protein homotetramerization-
GO:0055114IEA-oxidation-reduction process-
GO:0060041IEA-retina development in camera-type eye-
GO:0071353IEA-cellular response to interleukin-4-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
IMPDH2AKT110982810930578 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
IMPDH2AKT110671010930578 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
VHLIMPDH210982817353931 Affinity Capture-MS
VHLIMPDH211326917353931 Affinity Capture-MS
BCAR3IMPDH210982817353931 Affinity Capture-MS
BCAR3IMPDH211400017353931 Affinity Capture-MS
ATG5IMPDH210982817353931 Affinity Capture-MS
ATG5IMPDH211485917353931 Affinity Capture-MS
IKBKEIMPDH210982817353931 Affinity Capture-MS
IKBKEIMPDH211500017353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:109367
  • Data Attributes: MGI curated and HomoloGene calculated
No data