AutismKB 2.0

Annotation Details for IREB2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:IREB2 ( ACO3,FLJ23381,IRP2,IRP2AD )
Gene Full Name: iron-responsive element binding protein 2
Band: 15q25.1
Quick LinksEntrez ID:3658; OMIM: 147582; Uniprot ID:IREB2_HUMAN; ENSEMBL ID: ENSG00000136381; HGNC ID: 6115
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737NAS-cytoplasm7983023
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding7983023
GO:0003723TAS-RNA binding9924025
GO:0005515IPI-protein binding19762596
GO:0030350TAS-iron-responsive element binding9924025
GO:0030371IEA-translation repressor activity-
GO:0046872IEA-metal ion binding-
GO:0051539IEA-4 iron, 4 sulfur cluster binding-
GO ID Evidence Qualifier GO_term References
GO:0006826TAS-iron ion transport9924025
GO:0006879TAS-cellular iron ion homeostasis-
GO:0008152IEA-metabolic process-
GO:0017148IEA-negative regulation of translation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
YBX1IREB210986612192037 Affinity Capture-Western; Reconstituted Complex
YBX1IREB211095912192037 Affinity Capture-Western; Reconstituted Complex
UBCIREB210986612629548 15777842 Affinity Capture-Western
UBCIREB211316412629548 15777842 Affinity Capture-Western
RBCK1IREB211586212629548 Affinity Capture-Western; Biochemical Activity
RBCK1IREB210986612629548 Affinity Capture-Western; Biochemical Activity
VHLIREB211326915777842 Affinity Capture-Western
VHLIREB210986615777842 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
IREB2IREB_1967, IREB_941, IREB_exon16, IREB_exon21b, IREB_exon9, rs13180, rs2102264, rs2568484, rs2656070, rs4887060, rs954144 Gene overview in AlzGene
Gene Symbol Poly Names Gene overview in PDGene
IREB2IREB2_A852A, rs13180, rs2292116, rs3817092, rs8036042, rs954144 Gene overview in PDGene
No data
Animal Model Top
  • MGI ID: MGI:1928268
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved