AutismKB 2.0

Annotation Details for IRF2


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Basic Information Top
Gene Symbol:IRF2 ( DKFZp686F0244,IRF-2 )
Gene Full Name: interferon regulatory factor 2
Band: 4q35.1
Quick LinksEntrez ID:3660; OMIM: 147576; Uniprot ID:IRF2_HUMAN; ENSEMBL ID: ENSG00000168310; HGNC ID: 6117
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0005925IDA-focal adhesion-
GO ID Evidence Qualifier GO_term References
GO:0000977IMP-RNA polymerase II regulatory region sequence-specific DNA binding9540062
GO:0001228IMP-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding9540062
GO:0003677IDA-DNA binding9540062
GO:0003700IMP-transcription factor activity, sequence-specific DNA binding9540062
GO:0005515IPI-protein binding9540062
GO ID Evidence Qualifier GO_term References
GO:0000122TAS-negative regulation of transcription from RNA polymerase II promoter7507207
GO:0006355IMP-regulation of transcription, DNA-templated9540062
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0007596TAS-blood coagulation-
GO:0008283IEA-cell proliferation-
GO:0045944IMP-positive regulation of transcription from RNA polymerase II promoter9540062
GO:0060333TAS-interferon-gamma-mediated signaling pathway-
GO:0060337TAS-type I interferon signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
IRF2CSNK2A11098689213219 Biochemical Activity
IRF2CSNK2A11078419213219 Biochemical Activity
IRF2EP30010834711304541 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
IRF2EP30010986811304541 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
IRF2KAT2A10986810022868 Reconstituted Complex
IRF2KAT2A10891810022868 Reconstituted Complex
IRF2IRF81098687768900 Affinity Capture-Western
IRF2IRF81096217768900 Affinity Capture-Western
NFKB1IRF21108578550813 Reconstituted Complex
NFKB1IRF21098688550813 Reconstituted Complex
RELAIRF21098688550813 Reconstituted Complex
RELAIRF21119028550813 Reconstituted Complex
PRKACAIRF21115539213219 Biochemical Activity
PRKACAIRF21098689213219 Biochemical Activity
KAT2BIRF211437510022868 11304541 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
KAT2BIRF210986810022868 11304541 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
BRD7IRF211888311025449 Reconstituted Complex; Two-hybrid
BRD7IRF210986811025449 Reconstituted Complex; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:96591
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-4135'