AutismKB 2.0

Annotation Details for IRF5


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Basic Information Top
Gene Symbol:IRF5 ( SLEB10 )
Gene Full Name: interferon regulatory factor 5
Band: 7q32.1
Quick LinksEntrez ID:3663; OMIM: 607218; Uniprot ID:IRF5_HUMAN; ENSEMBL ID: ENSG00000128604; HGNC ID: 6120
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus22412986
GO:0005737IDA-cytoplasm22412986
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0000975IEA-regulatory region DNA binding-
GO:0001228IC-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-
GO:0005515IPI-protein binding20237317
GO:0043565IMP-sequence-specific DNA binding23332764
GO ID Evidence Qualifier GO_term References
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0032494IDA-response to peptidoglycan22412986
GO:0032495IDA-response to muramyl dipeptide22412986
GO:0032727IC-positive regulation of interferon-alpha production22412986
GO:0032728IC-positive regulation of interferon-beta production22412986
GO:0032735IC-positive regulation of interleukin-12 production22412986
GO:0043065IMP-positive regulation of apoptotic process22412986
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter12600985
GO:0051607IEA-defense response to virus-
GO:0060333TAS-interferon-gamma-mediated signaling pathway-
GO:0060337TAS-type I interferon signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
IRF5IRF310987111303025 Reconstituted Complex
IRF5IRF310986911303025 Reconstituted Complex
TRIM15IRF510987120211142 Two-hybrid
TRIM15IRF512462620211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1350924
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-2587'