AutismKB 2.0

Annotation Details for ITGA2B


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Basic Information Top
Gene Symbol:ITGA2B ( CD41,CD41B,GP2B,GPIIb,GTA,HPA3 )
Gene Full Name: integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
Band: 17q21.31
Quick LinksEntrez ID:3674; OMIM: 607759; Uniprot ID:ITA2B_HUMAN; ENSEMBL ID: ENSG00000005961; HGNC ID: 6138
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane2439501
GO:0005925IEA-focal adhesion-
GO:0008305IEA-integrin complex-
GO:0009897IEA-external side of plasma membrane-
GO:0009986IDA-cell surface23382103
GO:0031092TAS-platelet alpha granule membrane-
GO:0070062IDA-extracellular exosome15908444
GO:0072562IDA-blood microparticle22516433
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding14681217
GO:0042802IPI-identical protein binding11606749
GO:0046872IEA-metal ion binding-
GO:0050840IEA-extracellular matrix binding-
GO:0070051IEA-fibrinogen binding-
GO ID Evidence Qualifier GO_term References
GO:0002576TAS-platelet degranulation-
GO:0002687IEA-positive regulation of leukocyte migration-
GO:0007155TAS-cell adhesion2439501
GO:0007160IEA-cell-matrix adhesion-
GO:0007229IDA-integrin-mediated signaling pathway23382103
GO:0030198TAS-extracellular matrix organization-
GO:0070527IEA-platelet aggregation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ITGA2BAUP110703112042322 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ITGA2BAUP110988112042322 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ITGA2BCD3610738611238109 Affinity Capture-Western
ITGA2BCD3610988111238109 Affinity Capture-Western
ITGA2BCLNS1A10761715075326 Affinity Capture-Western; Reconstituted Complex
ITGA2BCLNS1A10988115075326 Affinity Capture-Western; Reconstituted Complex
ITGA2BCOL2A11076777520045 Reconstituted Complex
ITGA2BCOL2A11098817520045 Reconstituted Complex
ITGA2BF210844711487023 Reconstituted Complex
ITGA2BF210988111487023 Reconstituted Complex
ITGA2BGRB21091428631894 Reconstituted Complex
ITGA2BGRB21098818631894 Reconstituted Complex
RNF181ITGA2B11941115075326 18331836 Affinity Capture-MS; Reconstituted Complex
RNF181ITGA2B10988115075326 18331836 Affinity Capture-MS; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:96601
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-051031-1'